The dynamic analysis of a geared rotor-bearing system with time-varying gear mesh stiffness and pressure angle is presented in this paper. Although there are analyses for both of the gear and rotor-bearing system dynamics, the coupling effect of the time-varying mesh and geared rotor-bearing system is deficient. Therefore, the pressure angle and contact ratio of the geared rotor-bearing system are treated as time-varying variables in the proposed model while they were considered as constant in previous models. The gear mesh stiffness is varied with different contact ratios of the gear pair in the meshing process. The nonlinear equations of motion for the geared rotor-bearing system are obtained by applying Lagrange's equation and the dynamic responses are computed by using the Runge-Kutta numerical method. Numerical results of this study indicated that the proposed model provides realistic dynamic response of a geared rotor-bearing system.