Dynamic contrast-enhanced subtraction and delayed MRI of gastric tumors: Radiologic-pathologic correlation

Chien Kuo Wang, Yu Ting Kuo, Gin Chung Liu, Kun Bow Tsai, Yu Sheng Huang

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


Purpose: Our goal was to determine whether dynamic MR subtraction images could be used to detect and stage gastric tumors. Method: Dynamic MR subtraction images were prospectively performed in 20 patients without gastric lesions and in 39 patients with gastric tumors. The flat- or depressed-type early gastric cancers were excluded. The MR findings were assessed for layered pattern of the normal gastric wall, detectability of tumors, enhanced pattern of tumor, and depth of the tumor invasion. Surgical specimens were obtained from 30 of the patients with tumors, and histopathologic sections were made in the dynamic MR scanning direction. Results: The three-layered structure of the normal gastric wall was apparent in more of the dynamic MR subtraction images (60%) than of the nonsubtraction images (30%) in the control group. All 39 gastric tumors were detected by MRI. The intact inner layers overlying stromal tumors and outer layers interrupted by advanced gastric cancers were clear on the subtracted images. MRI accurately T-staged 88% of the gastric cancers. Conclusion: Dynamic MR subtraction images can be used to identify gastric tumors and to stage gastric cancers.

Original languageEnglish
Pages (from-to)872-877
Number of pages6
JournalJournal of computer assisted tomography
Issue number6
Publication statusPublished - 2000

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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