Early diagnosis and successful treatment of cryptococcus albidus keratitis

Yi Hsun Huang, I. Huang Lin, Tsung Chain Chang, Sung Huei Tseng

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


Cryptococcus albidus keratitis is a rare and difficult diagnosed disease. Here we report a case of C albidus keratitis early diagnosed by dot hybridization assay and successfully treated with intrastromal injection of Amphotericin B (AB). A 45-year-old man presented with left red eye for 2 days. The slit lamp examination exhibited deep corneal infiltrations. Smears and cultures were performed but revealed negative findings. Molecular detection of pathogens was performed by dot hybridization assay, and C albidus keratitis was diagnosed. Despite the identification of C albidus, the clinical condition still worsened due to deep corneal infiltration. After performing intrastromal injection of AB, the corneal infiltration gradually improved. C albidus is a rare cause of diseases in humans and should be considered as a potential pathogen of corneal ulcer. The prognosis of C albidus keratitis will improve if the condition is recognized early and treated properly.

Original languageEnglish
Article number885
JournalMedicine (United States)
Issue number19
Publication statusPublished - 2015 May 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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