The effects of aqueous extracts of raw and boiled garlic, onion and ginger were studied in vitro on the ADP-induced platelet aggregation using human platelet-rich plasma. Raw garlic extract completely inhibited ADP-induced platelet aggregation. Raw onion and ginger extracts also showed significantly inhibitory effects on the ADP-induced platelet aggregation, with 45.3% and 40.6% platelet aggregation of control, respectively. Boiled garlic, onion and ginger extracts revealed 56.4%, 64.0% and 83.4% platelet aggregation compared to 100% in the control, respectively. These results indicated that ADP-induced platelet aggregation was inhibited by garlic, onion and ginger extracts. The raw extract form demonstrated a stronger inhibitory effect than the boiled extract. The platelet aggregation inhibitory effects were the greatest for garlic, followed by ginger, and onion for both the raw and boiled forms.
|Number of pages||8|
|Journal||Nutritional Sciences Journal|
|Publication status||Published - 2000 Aug 26|
All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Nutrition and Dietetics