Effect of shear stress on cultivation of Bacillus thuringiensis for thuringiensin production

W. T. Wu, Y. L. Hsu, Y. F. Ko, L. L. Yao

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Cultivation of Bacillus thuringiensis for thuringiensin production is a mixed-growth-associated system. Cultivation conditions should be different during the cell growth stage and production stage. In this study, agitation speed and aeration rate were varied during the exponential growth phase and stationary phase in order to investigate the effect of shear stress via agitation on cultivation of B. thuringiensis for thuringiensin production. It was found that shear stress had a significant effect on thuringiensin production during the stationary phase. By decreasing the agitation speed during the stationary phase, product formation was increased up to 43%.

Original languageEnglish
Pages (from-to)175-177
Number of pages3
JournalApplied Microbiology and Biotechnology
Volume58
Issue number2
DOIs
Publication statusPublished - 2002

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology

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