Effects of inhibition of the B subunit of DNA gyrase on conjugation in Escherichia coli

  • D. C. Hooper
  • , J. S. Wolfson
  • , C. Tung
  • , K. S. Souza
  • , M. N. Swartz

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Antagonism of the DNA gyrase B subunit in the donor bacterium by coumermycin or thermal inactivation inhibited transfer of plasmid R64drd-11. Coumermycin also inhibited Hfr transfer, with kinetics after drug removal suggesting that transfer resumed from the point of inhibition, in contrast to inhibition with nalidixic acid, after which transfer reinitiated from the origin of transfer.

Original languageEnglish
Pages (from-to)2235-2237
Number of pages3
JournalJournal of Bacteriology
Volume171
Issue number4
DOIs
Publication statusPublished - 1989

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

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