Electrical Properties of HeLa Cells Based on Scalable 3D Interdigital Electrode Array

Fu Yu Chang; Ming Kun Chen; Min Haw Wang; Ling Sheng Jang

doi:10.1002/elan.201500624

Electrical Properties of HeLa Cells Based on Scalable 3D Interdigital Electrode Array

Fu Yu Chang, Ming Kun Chen, Min Haw Wang, Ling Sheng Jang

Department of Electrical Engineering

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

This study analyzed the electrical properties of a multiple-cells using the electric cell-substrate impedance sensing, a scalable three-dimensional electrode array and an equivalent circuit model (ECM). The experimental results validated the accuracy and validity of the extraction method for the ECM. The ECM simulation results using the electrical properties extracted by measuring 52 HeLa cells successfully forecasted the impedance magnitudes and phases for 15, 29, 78, and 98 HeLa cells. Comparing the ECM simulations and measurements, the maximum average errors in magnitude and phase were 3.06% and 4.67%, suggesting the number of HeLa cells can be classified by their electrical properties.

Original language	English
Pages (from-to)	962-969
Number of pages	8
Journal	Electroanalysis
Volume	28
Issue number	5
DOIs	https://doi.org/10.1002/elan.201500624
Publication status	Published - 2016 May 1

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Electrochemistry

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10.1002/elan.201500624

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title = "Electrical Properties of HeLa Cells Based on Scalable 3D Interdigital Electrode Array",

abstract = "This study analyzed the electrical properties of a multiple-cells using the electric cell-substrate impedance sensing, a scalable three-dimensional electrode array and an equivalent circuit model (ECM). The experimental results validated the accuracy and validity of the extraction method for the ECM. The ECM simulation results using the electrical properties extracted by measuring 52 HeLa cells successfully forecasted the impedance magnitudes and phases for 15, 29, 78, and 98 HeLa cells. Comparing the ECM simulations and measurements, the maximum average errors in magnitude and phase were 3.06% and 4.67%, suggesting the number of HeLa cells can be classified by their electrical properties.",

author = "Chang, {Fu Yu} and Chen, {Ming Kun} and Wang, {Min Haw} and Jang, {Ling Sheng}",

note = "Publisher Copyright: {\textcopyright} 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

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doi = "10.1002/elan.201500624",

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AU - Chang, Fu Yu

AU - Chen, Ming Kun

AU - Wang, Min Haw

AU - Jang, Ling Sheng

PY - 2016/5/1

Y1 - 2016/5/1

N2 - This study analyzed the electrical properties of a multiple-cells using the electric cell-substrate impedance sensing, a scalable three-dimensional electrode array and an equivalent circuit model (ECM). The experimental results validated the accuracy and validity of the extraction method for the ECM. The ECM simulation results using the electrical properties extracted by measuring 52 HeLa cells successfully forecasted the impedance magnitudes and phases for 15, 29, 78, and 98 HeLa cells. Comparing the ECM simulations and measurements, the maximum average errors in magnitude and phase were 3.06% and 4.67%, suggesting the number of HeLa cells can be classified by their electrical properties.

AB - This study analyzed the electrical properties of a multiple-cells using the electric cell-substrate impedance sensing, a scalable three-dimensional electrode array and an equivalent circuit model (ECM). The experimental results validated the accuracy and validity of the extraction method for the ECM. The ECM simulation results using the electrical properties extracted by measuring 52 HeLa cells successfully forecasted the impedance magnitudes and phases for 15, 29, 78, and 98 HeLa cells. Comparing the ECM simulations and measurements, the maximum average errors in magnitude and phase were 3.06% and 4.67%, suggesting the number of HeLa cells can be classified by their electrical properties.

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JO - Electroanalysis

JF - Electroanalysis

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ER -

Electrical Properties of HeLa Cells Based on Scalable 3D Interdigital Electrode Array

Abstract

All Science Journal Classification (ASJC) codes

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