Electrical Properties of HeLa Cells Based on Scalable 3D Interdigital Electrode Array

Fu Yu Chang, Ming Kun Chen, Min Haw Wang, Ling-Sheng Jang

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

This study analyzed the electrical properties of a multiple-cells using the electric cell-substrate impedance sensing, a scalable three-dimensional electrode array and an equivalent circuit model (ECM). The experimental results validated the accuracy and validity of the extraction method for the ECM. The ECM simulation results using the electrical properties extracted by measuring 52 HeLa cells successfully forecasted the impedance magnitudes and phases for 15, 29, 78, and 98 HeLa cells. Comparing the ECM simulations and measurements, the maximum average errors in magnitude and phase were 3.06% and 4.67%, suggesting the number of HeLa cells can be classified by their electrical properties.

Original languageEnglish
Pages (from-to)962-969
Number of pages8
JournalElectroanalysis
Volume28
Issue number5
DOIs
Publication statusPublished - 2016 May 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Electrochemistry

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