@article{a843d05cdaa74df0bc378b7b4ef9afc6,
title = "Electrical Properties of HeLa Cells Based on Scalable 3D Interdigital Electrode Array",
abstract = "This study analyzed the electrical properties of a multiple-cells using the electric cell-substrate impedance sensing, a scalable three-dimensional electrode array and an equivalent circuit model (ECM). The experimental results validated the accuracy and validity of the extraction method for the ECM. The ECM simulation results using the electrical properties extracted by measuring 52 HeLa cells successfully forecasted the impedance magnitudes and phases for 15, 29, 78, and 98 HeLa cells. Comparing the ECM simulations and measurements, the maximum average errors in magnitude and phase were 3.06% and 4.67%, suggesting the number of HeLa cells can be classified by their electrical properties.",
author = "Chang, {Fu Yu} and Chen, {Ming Kun} and Wang, {Min Haw} and Jang, {Ling Sheng}",
note = "Funding Information: This study was financially supported by the National Science Council of Taiwan (NSC 101 2221-E-006-004-MY3) and made use of shared facilities provided under the Program of Top 100 Universities Advancement funded by the Ministry of Education in Taiwan. The authors would like to thank the Center for Micro/Nano Science and Technology at National Cheng Kung University, Tainan, Taiwan, for access to equipment throughout the duration of this study and for their general technical support. The authors would also like to thank Prof. Hao-Ven Wang, Department of Life Sciences National Cheng Kung University, for providing the equipment and environment for cell culture. Publisher Copyright: {\textcopyright} 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2016",
month = may,
day = "1",
doi = "10.1002/elan.201500624",
language = "English",
volume = "28",
pages = "962--969",
journal = "Electroanalysis",
issn = "1040-0397",
publisher = "Wiley-VCH Verlag",
number = "5",
}