Electrochemical oxidation of histidine at an anodic oxidized boron-doped diamond electrode in neutral solution

Li Chia Chen, Chia Chin Chang, Hsien Chang Chang

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28 Citations (Scopus)

Abstract

Electrochemical oxidation of histidine (His) at an anodic oxidized boron-doped diamond electrode (AOBDDE) was performed. A significant peak of His oxidation is observed at about +1.5 V vs. Ag/AgCl, however, the response current was inhibited due to strong His-oxidized product adsorption onto the electrode surface. The characteristics of the His-oxidized product adsorbed onto the electrode surface were investigated by studying the electrochemical behavior of the Fe(CN)64- redox reaction using cycle voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Both CV and EIS results showed a decrease in the sum of transfer coefficients and an increase in the electron transfer resistance, which indicate that the adsorption film is a non-conductive film. The most possible active site locations for the AOBDDE for His oxidation are within these low-lying polycrystallite AOBDDE surface regions. The results from Raman and X-ray photoelectron spectroscopy offer strong evidence of the imidazole ring reaction from His. Experiments confirmed that the adsorbed film can be removed and the electrode surface reactivated using brief polarization at +2.5 V.

Original languageEnglish
Pages (from-to)2883-2889
Number of pages7
JournalElectrochimica Acta
Volume53
Issue number6
DOIs
Publication statusPublished - 2008 Feb 15

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Electrochemistry

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