Electrokinetic micromixing of charged and non-charged samples near nano-microchannel junction

Pin Hsien Chiu, Chih Chang Chang, Ruey Jen Yang

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


A nano-microchannel flow mixer comprising a polydimethylsiloxane (PDMS) microchannel and a Nafion nanoporous membrane is fabricated. It is shown that when an electric field is applied across the device, an ion enrichment/ion depletion effect occurs near the nano-microchannel junction. The mixing performance of the proposed device is examined for three different samples, namely fluorescein (negatively charged), Rhodamine 6G (positively charged), and Rhodamine B (electroneutral). It is shown that a mixing effect is obtained only for the Rhodamine B solution. Thus, it is inferred that nano-microchannel devices such as that presented in this study and those presented in the literature are unsuitable for biomolecule detection applications since such molecules are generally charged.

Original languageEnglish
Pages (from-to)839-844
Number of pages6
JournalMicrofluidics and Nanofluidics
Issue number5
Publication statusPublished - 2013 May

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Materials Chemistry


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