Electromagnetic thermotherapy system with needle arrays: A practical tool for the removal of cancerous tumors

Sheng Chieh Huang, Jui Wen Kang, Hung Wen Tsai, Yan Shen Shan, Xi Zhang Lin, Gwo Bin Lee

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Thermotherapy has been a promising method to treat tumor. In recent years, electromagnetic thermotherapy (EMT) has been extensively investigated and holds the potential for a variety of medical applications including for cancer treatment when combined with minimally invasive surgery approach. In this study, an alternating electromagnetic frequency was provided by an EMT system to heat up stainless steel needle arrays which were inserted into the target tumor to a high temperature, therefore leading to local ablation of the tumor. A new two-section needle-array apparatus was further demonstrated to encompass the tumor to prevent the tumor cells to spread after the treatment process. By using the needle-array insertion apparatus, there is no limitation of the treatment area; this method could, therefore, be applied for tumors that are larger than 6 cm. It was first successfully demonstrated in the in vitro experiments on porcine livers. Then an in vivo experiment was directly conducted on pigs. The two-section needle array incorporated with the needle-array apparatus and EMT was demonstrated to be promising for no-touch isolation treatment of cancerous tumors.

Original languageEnglish
Article number6645388
Pages (from-to)598-605
Number of pages8
JournalIEEE Transactions on Biomedical Engineering
Volume61
Issue number2
DOIs
Publication statusPublished - 2014 Feb 1

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Needles
Tumors
Oncology
Medical applications
Ablation
Liver
Surgery
Stainless steel
Experiments
Cells

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

Cite this

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title = "Electromagnetic thermotherapy system with needle arrays: A practical tool for the removal of cancerous tumors",
abstract = "Thermotherapy has been a promising method to treat tumor. In recent years, electromagnetic thermotherapy (EMT) has been extensively investigated and holds the potential for a variety of medical applications including for cancer treatment when combined with minimally invasive surgery approach. In this study, an alternating electromagnetic frequency was provided by an EMT system to heat up stainless steel needle arrays which were inserted into the target tumor to a high temperature, therefore leading to local ablation of the tumor. A new two-section needle-array apparatus was further demonstrated to encompass the tumor to prevent the tumor cells to spread after the treatment process. By using the needle-array insertion apparatus, there is no limitation of the treatment area; this method could, therefore, be applied for tumors that are larger than 6 cm. It was first successfully demonstrated in the in vitro experiments on porcine livers. Then an in vivo experiment was directly conducted on pigs. The two-section needle array incorporated with the needle-array apparatus and EMT was demonstrated to be promising for no-touch isolation treatment of cancerous tumors.",
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AU - Huang, Sheng Chieh

AU - Kang, Jui Wen

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AU - Shan, Yan Shen

AU - Lin, Xi Zhang

AU - Lee, Gwo Bin

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