Elevation of soluble adhesion molecules is associated with the severity of myocardial damage in acute myocardial infarction

Yi Heng Li, Jeng Kai Teng, Wei Chun Tsai, Liang Miin Tsai, Li Jen Lin, Jyh Hong Chen

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

In 20 patients with acute myocardial infarction, blood samples were taken to study the serial changes in the soluble intracellular adhesion molecule-1 (ICAM-1), vascular cellular adhesion molecule -1 (VCAM-1) and E- selectin. Results indicated that soluble ICAM-1 increased significantly and persisted throughout the study period; however, soluble E-selectin was significantly elevated only transiently and decreased rapidly thereafter, and the VCAM-1 did not increased during entire study period. There was a significant correlation between the levels of ICAM-1, E-selectin 6 hours after admission, and peak creatine kinase level; the levels of ICAM-1 and E- selectin were also positively correlated with total leukocyte count at admission.

Original languageEnglish
Pages (from-to)1218-1221
Number of pages4
JournalAmerican Journal of Cardiology
Volume80
Issue number9
DOIs
Publication statusPublished - 1997 Nov 1

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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