In 20 patients with acute myocardial infarction, blood samples were taken to study the serial changes in the soluble intracellular adhesion molecule-1 (ICAM-1), vascular cellular adhesion molecule -1 (VCAM-1) and E- selectin. Results indicated that soluble ICAM-1 increased significantly and persisted throughout the study period; however, soluble E-selectin was significantly elevated only transiently and decreased rapidly thereafter, and the VCAM-1 did not increased during entire study period. There was a significant correlation between the levels of ICAM-1, E-selectin 6 hours after admission, and peak creatine kinase level; the levels of ICAM-1 and E- selectin were also positively correlated with total leukocyte count at admission.
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine