Elimination of hypercapnia may postpone the clinical presentations of malignant hyperthermia

A case report

Yuan Yi Chia, Yen-Chin Liu, Ming Chan Lee, Yuan Lo, Kong Liu

Research output: Contribution to journalArticle

Abstract

Malignant hyperthermia is a rare complication in clinical anesthesia, especially associated with the administration of succinylcholine or inhalation anesthetics. A 19-year-old patient, suffering from traumatic mandible fracture, underwent open reduction under general anesthesia. Unfortunately, following administration of succinylcholine, he also suffered severe facial twitch and the first episode of hypercapnia. After adequate management, the symptoms subsided. However, two hours later, the hypercapnia recurred, combined with progressive elevation of body temperature. After administration of intravenous dantrolene 120 mg, the patient's condition became stable and the procedure was completed without sequelae. As the muscle contracture test is not available in Taiwan, the clinical grading scale is presented as an alternative diagnostic method for malignant hyperthermia.

Original languageEnglish
Pages (from-to)230-234
Number of pages5
JournalChinese Medical Journal (Taipei)
Volume61
Issue number4
Publication statusPublished - 1998 Apr

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Malignant Hyperthermia
Succinylcholine
Hypercapnia
Dantrolene
Inhalation Anesthetics
Contracture
Body Temperature
Mandible
Taiwan
Intravenous Administration
General Anesthesia
Anesthesia
Muscles
Open Fracture Reduction

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "Elimination of hypercapnia may postpone the clinical presentations of malignant hyperthermia: A case report",
abstract = "Malignant hyperthermia is a rare complication in clinical anesthesia, especially associated with the administration of succinylcholine or inhalation anesthetics. A 19-year-old patient, suffering from traumatic mandible fracture, underwent open reduction under general anesthesia. Unfortunately, following administration of succinylcholine, he also suffered severe facial twitch and the first episode of hypercapnia. After adequate management, the symptoms subsided. However, two hours later, the hypercapnia recurred, combined with progressive elevation of body temperature. After administration of intravenous dantrolene 120 mg, the patient's condition became stable and the procedure was completed without sequelae. As the muscle contracture test is not available in Taiwan, the clinical grading scale is presented as an alternative diagnostic method for malignant hyperthermia.",
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Elimination of hypercapnia may postpone the clinical presentations of malignant hyperthermia : A case report. / Chia, Yuan Yi; Liu, Yen-Chin; Lee, Ming Chan; Lo, Yuan; Liu, Kong.

In: Chinese Medical Journal (Taipei), Vol. 61, No. 4, 04.1998, p. 230-234.

Research output: Contribution to journalArticle

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