Emergence of uncommon emm types of Streptococcus pyogenes among adult patients in southern Taiwan

Chuan Chiang-Ni, An Bang Wu, Ching Chuan Liu, Kow Ton Chen, Yee Shin Lin, Woei Jer Chuang, Hsin Yi Fang, Jiunn Jong Wu

Research output: Contribution to journalArticle

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Abstract

Background: Streptococcus pyogenes isolated from adult patients during a 12-year period in southern Taiwan were analyzed to estimate the distribution of emm types and their correlation with disease manifestations and patient age. Methods: Three hundred thirty-four invasive and noninvasive isolates collected from patients older than 20 years between 1997 and 2008 at National Cheng Kung University Hospital were included for emm typing. A correlation between emm type, disease manifestations, and patient ages was analyzed. Results: The nine most prevalent types were emm11, emm12, emm4, emm1, Sp9458/VT8, emm81, emm106, emm13, and emm75. Formerly rare emm types, including emm11, emm81, and emm102, emerged dramatically after 2004 in southern Taiwan. Type emm11 was significantly associated with both superficial infections and cellulitis. In addition, types emm13, emm81, and emm106 were more prevalent in patients older than 50 years and significantly associated with specific invasive disease manifestation. Conclusion: These results suggest new emm types (emm11, emm81, and emm102) of S  pyogenes were introduced into the adult population in southern Taiwan after 2004. The rarely reported emm types, including emm13, emm81, and emm106, caused invasive diseases more often in adult patients.

Original languageEnglish
Pages (from-to)424-429
Number of pages6
JournalJournal of Microbiology, Immunology and Infection
Volume44
Issue number6
DOIs
Publication statusPublished - 2011 Dec 1

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Streptococcus pyogenes
Taiwan
Cellulitis
Infection
Population

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

Cite this

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title = "Emergence of uncommon emm types of Streptococcus pyogenes among adult patients in southern Taiwan",
abstract = "Background: Streptococcus pyogenes isolated from adult patients during a 12-year period in southern Taiwan were analyzed to estimate the distribution of emm types and their correlation with disease manifestations and patient age. Methods: Three hundred thirty-four invasive and noninvasive isolates collected from patients older than 20 years between 1997 and 2008 at National Cheng Kung University Hospital were included for emm typing. A correlation between emm type, disease manifestations, and patient ages was analyzed. Results: The nine most prevalent types were emm11, emm12, emm4, emm1, Sp9458/VT8, emm81, emm106, emm13, and emm75. Formerly rare emm types, including emm11, emm81, and emm102, emerged dramatically after 2004 in southern Taiwan. Type emm11 was significantly associated with both superficial infections and cellulitis. In addition, types emm13, emm81, and emm106 were more prevalent in patients older than 50 years and significantly associated with specific invasive disease manifestation. Conclusion: These results suggest new emm types (emm11, emm81, and emm102) of S  pyogenes were introduced into the adult population in southern Taiwan after 2004. The rarely reported emm types, including emm13, emm81, and emm106, caused invasive diseases more often in adult patients.",
author = "Chuan Chiang-Ni and Wu, {An Bang} and Liu, {Ching Chuan} and Chen, {Kow Ton} and Lin, {Yee Shin} and Chuang, {Woei Jer} and Fang, {Hsin Yi} and Wu, {Jiunn Jong}",
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Emergence of uncommon emm types of Streptococcus pyogenes among adult patients in southern Taiwan. / Chiang-Ni, Chuan; Wu, An Bang; Liu, Ching Chuan; Chen, Kow Ton; Lin, Yee Shin; Chuang, Woei Jer; Fang, Hsin Yi; Wu, Jiunn Jong.

In: Journal of Microbiology, Immunology and Infection, Vol. 44, No. 6, 01.12.2011, p. 424-429.

Research output: Contribution to journalArticle

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T1 - Emergence of uncommon emm types of Streptococcus pyogenes among adult patients in southern Taiwan

AU - Chiang-Ni, Chuan

AU - Wu, An Bang

AU - Liu, Ching Chuan

AU - Chen, Kow Ton

AU - Lin, Yee Shin

AU - Chuang, Woei Jer

AU - Fang, Hsin Yi

AU - Wu, Jiunn Jong

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N2 - Background: Streptococcus pyogenes isolated from adult patients during a 12-year period in southern Taiwan were analyzed to estimate the distribution of emm types and their correlation with disease manifestations and patient age. Methods: Three hundred thirty-four invasive and noninvasive isolates collected from patients older than 20 years between 1997 and 2008 at National Cheng Kung University Hospital were included for emm typing. A correlation between emm type, disease manifestations, and patient ages was analyzed. Results: The nine most prevalent types were emm11, emm12, emm4, emm1, Sp9458/VT8, emm81, emm106, emm13, and emm75. Formerly rare emm types, including emm11, emm81, and emm102, emerged dramatically after 2004 in southern Taiwan. Type emm11 was significantly associated with both superficial infections and cellulitis. In addition, types emm13, emm81, and emm106 were more prevalent in patients older than 50 years and significantly associated with specific invasive disease manifestation. Conclusion: These results suggest new emm types (emm11, emm81, and emm102) of S  pyogenes were introduced into the adult population in southern Taiwan after 2004. The rarely reported emm types, including emm13, emm81, and emm106, caused invasive diseases more often in adult patients.

AB - Background: Streptococcus pyogenes isolated from adult patients during a 12-year period in southern Taiwan were analyzed to estimate the distribution of emm types and their correlation with disease manifestations and patient age. Methods: Three hundred thirty-four invasive and noninvasive isolates collected from patients older than 20 years between 1997 and 2008 at National Cheng Kung University Hospital were included for emm typing. A correlation between emm type, disease manifestations, and patient ages was analyzed. Results: The nine most prevalent types were emm11, emm12, emm4, emm1, Sp9458/VT8, emm81, emm106, emm13, and emm75. Formerly rare emm types, including emm11, emm81, and emm102, emerged dramatically after 2004 in southern Taiwan. Type emm11 was significantly associated with both superficial infections and cellulitis. In addition, types emm13, emm81, and emm106 were more prevalent in patients older than 50 years and significantly associated with specific invasive disease manifestation. Conclusion: These results suggest new emm types (emm11, emm81, and emm102) of S  pyogenes were introduced into the adult population in southern Taiwan after 2004. The rarely reported emm types, including emm13, emm81, and emm106, caused invasive diseases more often in adult patients.

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