Engineered dermal scaffold for improved skin regeneration

Lynn Ling-Huei Huang, H. C. Lin, M. H. Tai, Yang-Gao Wang, G. M. Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Two sets of animal study were performed on the dorsal full-thickness skin wounds of guinea pigs to evaluate the efficacy of series of engineered scaffolds derived from porcine dermis. A porous collagen matrix incorporated with hyaluronan (PCHM) was developed and proved to heal full-thickness skin wounds with indistinguishable collagen architecture from the normal peripheral dermis. A second set of animal study aiming at investigating the efficacy of combination of bFGF and PCHM on wound healing concluded that PCHM-bFGF further improved angiogenesis and fibroplasias in the wound sites and greatly enhanced the regeneration of skin.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004 Dec 1
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period04-05-1704-05-21

Fingerprint

Scaffolds (biology)
Skin
Collagen
Animals

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Huang, L. L-H., Lin, H. C., Tai, M. H., Wang, Y-G., & Liu, G. M. (2004). Engineered dermal scaffold for improved skin regeneration. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).
Huang, Lynn Ling-Huei ; Lin, H. C. ; Tai, M. H. ; Wang, Yang-Gao ; Liu, G. M. / Engineered dermal scaffold for improved skin regeneration. Transactions - 7th World Biomaterials Congress. 2004. (Transactions - 7th World Biomaterials Congress).
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Huang, LL-H, Lin, HC, Tai, MH, Wang, Y-G & Liu, GM 2004, Engineered dermal scaffold for improved skin regeneration. in Transactions - 7th World Biomaterials Congress. Transactions - 7th World Biomaterials Congress, Transactions - 7th World Biomaterials Congress, Sydney, Australia, 04-05-17.

Engineered dermal scaffold for improved skin regeneration. / Huang, Lynn Ling-Huei; Lin, H. C.; Tai, M. H.; Wang, Yang-Gao; Liu, G. M.

Transactions - 7th World Biomaterials Congress. 2004. (Transactions - 7th World Biomaterials Congress).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Huang LL-H, Lin HC, Tai MH, Wang Y-G, Liu GM. Engineered dermal scaffold for improved skin regeneration. In Transactions - 7th World Biomaterials Congress. 2004. (Transactions - 7th World Biomaterials Congress).