Engineered dermal scaffold for improved skin regeneration

Lynn Ling-Huei Huang, H. C. Lin, M. H. Tai, Yang-Gao Wang, G. M. Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Two sets of animal study were performed on the dorsal full-thickness skin wounds of guinea pigs to evaluate the efficacy of series of engineered scaffolds derived from porcine dermis. A porous collagen matrix incorporated with hyaluronan (PCHM) was developed and proved to heal full-thickness skin wounds with indistinguishable collagen architecture from the normal peripheral dermis. A second set of animal study aiming at investigating the efficacy of combination of bFGF and PCHM on wound healing concluded that PCHM-bFGF further improved angiogenesis and fibroplasias in the wound sites and greatly enhanced the regeneration of skin.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004 Dec 1
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period04-05-1704-05-21

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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