Enterovirus 71, One Virus and Many Stories

Research output: Contribution to journalReview article

31 Citations (Scopus)

Abstract

Enterovirus 71 (EV71) has emerged as a significant cause of brainstem encephalitis and acute flaccid paralysis in Taiwan. It may be complicated by autonomic nervous system dysregulation and pulmonary edema (PE). Cytokines in the central nervous system and systemic inflammatory responses play important roles in the pathogenesis of EV71-associated PE. Pathogenesis-based management with intravenous immunoglobulin and milrinone has been associated with reduced mortality in children with severe EV71 infections.

Original languageEnglish
Pages (from-to)113-115
Number of pages3
JournalPediatrics and Neonatology
Volume49
Issue number4
DOIs
Publication statusPublished - 2008 Aug 1

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Enterovirus
Pulmonary Edema
Enterovirus Infections
Milrinone
Viruses
Child Mortality
Intravenous Immunoglobulins
Autonomic Nervous System
Encephalitis
Taiwan
Paralysis
Brain Stem
Central Nervous System
Cytokines

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

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title = "Enterovirus 71, One Virus and Many Stories",
abstract = "Enterovirus 71 (EV71) has emerged as a significant cause of brainstem encephalitis and acute flaccid paralysis in Taiwan. It may be complicated by autonomic nervous system dysregulation and pulmonary edema (PE). Cytokines in the central nervous system and systemic inflammatory responses play important roles in the pathogenesis of EV71-associated PE. Pathogenesis-based management with intravenous immunoglobulin and milrinone has been associated with reduced mortality in children with severe EV71 infections.",
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Enterovirus 71, One Virus and Many Stories. / Wang, Shih Min; Ho, Tzong Shiann; Shen, Ching Fen; Liu, Ching Chuan.

In: Pediatrics and Neonatology, Vol. 49, No. 4, 01.08.2008, p. 113-115.

Research output: Contribution to journalReview article

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AB - Enterovirus 71 (EV71) has emerged as a significant cause of brainstem encephalitis and acute flaccid paralysis in Taiwan. It may be complicated by autonomic nervous system dysregulation and pulmonary edema (PE). Cytokines in the central nervous system and systemic inflammatory responses play important roles in the pathogenesis of EV71-associated PE. Pathogenesis-based management with intravenous immunoglobulin and milrinone has been associated with reduced mortality in children with severe EV71 infections.

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