TY - JOUR
T1 - Epidemiology of childhood intussusception and determinants of recurrence and operation
T2 - Analysis of national health insurance data between 1998 and 2007 in Taiwan
AU - Chen, Solomon Chih Cheng
AU - Wang, Jung Der
AU - Hsu, Hong Yuan
AU - Leong, Mee Mee
AU - Tok, Teck Siang
AU - Chin, Yow Yue
N1 - Funding Information:
This study is based in part on data from the National Health Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health, and managed by National Health Research Institutes. The interpretation and conclusions contained herein do not represent those of the Bureau of National Health Insurance, Department of Health or National Health Research Institutes of Taiwan. The authors sincerely thank Ms Yu-Yin Chang for her great assistance on data management.
PY - 2010/10
Y1 - 2010/10
N2 - Background To study the epidemiology of childhood intussusception and risk factors of recurrence and operation based on a nationwide data. Methods Children with hospitalization due to intussusception (ICD9: 560.0) between 1998 and 2007 were identified from a national health insurance database. The incidence was calculated by age, sex, calendar year and month of admission. Recurrence and operation rates, duration and costs of hospitalization were analyzed. Results A total of 8217 intussusception-related hospitalizations were identified in 7541 children. The incidence of intussusception peaked between 3 and 36 months of age. Male -to-female incidence rate ratio increased from 1.31 in the first year to 2.52 in the ninth year of life. The overall recurrence and operation rates were 7.9 and 24.9, respectively. In children less than 1 year old, the recurrence rate was 10.1, which decreased to 5.3 in children over 3 years old. Multiple logistic regression analysis showed that children receiving operation had a significantly lower risk of recurrence with an odds ratio (95 confidence interval) of 0.31 (0.24-0.41) after controlling for age and sex. There are significantly more cases occurring during the warmer months between May and October compared to the cooler months between November and April. Conclusions There was a male predominance of intussusception with a dynamic male-to-female incidence rate ratio. Children under 1 year of age have the highest recurrence and operation rates. Seasonal variation of intussusception was suspected in Taiwan.
AB - Background To study the epidemiology of childhood intussusception and risk factors of recurrence and operation based on a nationwide data. Methods Children with hospitalization due to intussusception (ICD9: 560.0) between 1998 and 2007 were identified from a national health insurance database. The incidence was calculated by age, sex, calendar year and month of admission. Recurrence and operation rates, duration and costs of hospitalization were analyzed. Results A total of 8217 intussusception-related hospitalizations were identified in 7541 children. The incidence of intussusception peaked between 3 and 36 months of age. Male -to-female incidence rate ratio increased from 1.31 in the first year to 2.52 in the ninth year of life. The overall recurrence and operation rates were 7.9 and 24.9, respectively. In children less than 1 year old, the recurrence rate was 10.1, which decreased to 5.3 in children over 3 years old. Multiple logistic regression analysis showed that children receiving operation had a significantly lower risk of recurrence with an odds ratio (95 confidence interval) of 0.31 (0.24-0.41) after controlling for age and sex. There are significantly more cases occurring during the warmer months between May and October compared to the cooler months between November and April. Conclusions There was a male predominance of intussusception with a dynamic male-to-female incidence rate ratio. Children under 1 year of age have the highest recurrence and operation rates. Seasonal variation of intussusception was suspected in Taiwan.
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U2 - 10.1016/S1875-9572(10)60055-1
DO - 10.1016/S1875-9572(10)60055-1
M3 - Article
C2 - 20951359
AN - SCOPUS:77958013717
SN - 1875-9572
VL - 51
SP - 285
EP - 291
JO - Pediatrics and Neonatology
JF - Pediatrics and Neonatology
IS - 5
ER -