TY - JOUR
T1 - Evaluation of background persistent organic pollutant levels in human from Taiwan
T2 - Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls
AU - Hsu, Jing Fang
AU - Lee, Ching Chang
AU - Su, Huei Jen
AU - Chen, Hsiu Ling
AU - Yang, Shu Yao
AU - Liao, Pao Chi
N1 - Funding Information:
This work was supported by grants from the Bureau of Food and Drug Analysis, Department of Health, Executive Yuan, Taiwan, the National Science Council of Taiwan (NSC95-2113-M-006-006 and NSC96-2628-M-006-005) and National Cheng Kung University Project of Promoting Academic Excellence & Developing World Class Research Centers from Ministry of Education of Taiwan. The authors greatly appreciated the assistance of Mr. Pang-Wei Chen for the preparation of Fig. 1 .
PY - 2009/1
Y1 - 2009/1
N2 - This study was intended to determine the background levels of PCDD/PCDFs and PCBs in the Taiwanese population and to investigate factors potentially related to PCDD/PCDF and PCB levels. The levels of seventeen PCDD/PCDFs in the 251 serum samples collected from the general population in Taiwan ranged from 4.92 to 26.7 pg WHO1998-TEQ/g lipid (median: 11.5) and those of the twelve dioxin-like PCBs ranged between 1.74 and 21.6 pg WHO1998-TEQ/g lipid (median: 6.14). Five factors, age, gender, region of residence, dietary status, and smoking status, showed statistically significant association with the TEQ level of PCDD/PCDFs. The TEQ level of PCBs was statistically associated with age only, but not with the other four factors. The trends observed between age and the levels of PCDD/PCDFs and PCBs were not parallel in young subjects (< 30 years old) and old subjects (> 30 years old). The levels of PCDD/PCDFs and PCBs increased by 0.16 and 0.03 WHO1998-TEQ/g lipid per year for subjects above the age of 30, but there was no evidence of any association between age and the levels for subjects below the age of 30 years. These factors should be considered when investigating relationships between background serum levels of persistent organic pollutants and parameters associated with exposure sources or health outcomes.
AB - This study was intended to determine the background levels of PCDD/PCDFs and PCBs in the Taiwanese population and to investigate factors potentially related to PCDD/PCDF and PCB levels. The levels of seventeen PCDD/PCDFs in the 251 serum samples collected from the general population in Taiwan ranged from 4.92 to 26.7 pg WHO1998-TEQ/g lipid (median: 11.5) and those of the twelve dioxin-like PCBs ranged between 1.74 and 21.6 pg WHO1998-TEQ/g lipid (median: 6.14). Five factors, age, gender, region of residence, dietary status, and smoking status, showed statistically significant association with the TEQ level of PCDD/PCDFs. The TEQ level of PCBs was statistically associated with age only, but not with the other four factors. The trends observed between age and the levels of PCDD/PCDFs and PCBs were not parallel in young subjects (< 30 years old) and old subjects (> 30 years old). The levels of PCDD/PCDFs and PCBs increased by 0.16 and 0.03 WHO1998-TEQ/g lipid per year for subjects above the age of 30, but there was no evidence of any association between age and the levels for subjects below the age of 30 years. These factors should be considered when investigating relationships between background serum levels of persistent organic pollutants and parameters associated with exposure sources or health outcomes.
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U2 - 10.1016/j.envint.2008.06.010
DO - 10.1016/j.envint.2008.06.010
M3 - Article
C2 - 18678409
AN - SCOPUS:56949088293
SN - 0160-4120
VL - 35
SP - 33
EP - 42
JO - Environment international
JF - Environment international
IS - 1
ER -