Evidence of time-varying myocardial contribution by in vivo magnitude and phase measurement in mice

Chia-Ling Wei, Jonathan W. Valvano, Marc D. Feldman, Anil Kottam, David Altman, Karthik Raghavan, Daniel J. Fernandez, Maricela Reyes, Daniel Escobedo, John A. Pearce

Research output: Contribution to journalConference article

7 Citations (Scopus)

Abstract

Cardiac volume can be estimated by a conductance catheter system. Both blood and myocardium are conductive, but only the blood conductance is desired. Therefore, the parallel myocardium contribution should be removed from the total measured conductance. Several methods have been developed to estimate the contribution from myocardium, and they only determine a single steady state value for the parallel contribution. Besides, myocardium was treated as purely resistive or mainly capacitive when estimating the myocardial contribution. We question these assumptions and propose that the myocardium is both resistive and capacitive, and its contribution changes during a single cardiac cycle. In vivo magnitude and phase experiments were performed in mice to confirm this hypothesis.

Original languageEnglish
Pages (from-to)3674-3677
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume26 V
Publication statusPublished - 2004 Dec 1
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: 2004 Sep 12004 Sep 5

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Phase measurement
Myocardium
Blood
Catheters
Cardiac Volume
Experiments

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Wei, Chia-Ling ; Valvano, Jonathan W. ; Feldman, Marc D. ; Kottam, Anil ; Altman, David ; Raghavan, Karthik ; Fernandez, Daniel J. ; Reyes, Maricela ; Escobedo, Daniel ; Pearce, John A. / Evidence of time-varying myocardial contribution by in vivo magnitude and phase measurement in mice. In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2004 ; Vol. 26 V. pp. 3674-3677.
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abstract = "Cardiac volume can be estimated by a conductance catheter system. Both blood and myocardium are conductive, but only the blood conductance is desired. Therefore, the parallel myocardium contribution should be removed from the total measured conductance. Several methods have been developed to estimate the contribution from myocardium, and they only determine a single steady state value for the parallel contribution. Besides, myocardium was treated as purely resistive or mainly capacitive when estimating the myocardial contribution. We question these assumptions and propose that the myocardium is both resistive and capacitive, and its contribution changes during a single cardiac cycle. In vivo magnitude and phase experiments were performed in mice to confirm this hypothesis.",
author = "Chia-Ling Wei and Valvano, {Jonathan W.} and Feldman, {Marc D.} and Anil Kottam and David Altman and Karthik Raghavan and Fernandez, {Daniel J.} and Maricela Reyes and Daniel Escobedo and Pearce, {John A.}",
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Wei, C-L, Valvano, JW, Feldman, MD, Kottam, A, Altman, D, Raghavan, K, Fernandez, DJ, Reyes, M, Escobedo, D & Pearce, JA 2004, 'Evidence of time-varying myocardial contribution by in vivo magnitude and phase measurement in mice', Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 26 V, pp. 3674-3677.

Evidence of time-varying myocardial contribution by in vivo magnitude and phase measurement in mice. / Wei, Chia-Ling; Valvano, Jonathan W.; Feldman, Marc D.; Kottam, Anil; Altman, David; Raghavan, Karthik; Fernandez, Daniel J.; Reyes, Maricela; Escobedo, Daniel; Pearce, John A.

In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, Vol. 26 V, 01.12.2004, p. 3674-3677.

Research output: Contribution to journalConference article

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T1 - Evidence of time-varying myocardial contribution by in vivo magnitude and phase measurement in mice

AU - Wei, Chia-Ling

AU - Valvano, Jonathan W.

AU - Feldman, Marc D.

AU - Kottam, Anil

AU - Altman, David

AU - Raghavan, Karthik

AU - Fernandez, Daniel J.

AU - Reyes, Maricela

AU - Escobedo, Daniel

AU - Pearce, John A.

PY - 2004/12/1

Y1 - 2004/12/1

N2 - Cardiac volume can be estimated by a conductance catheter system. Both blood and myocardium are conductive, but only the blood conductance is desired. Therefore, the parallel myocardium contribution should be removed from the total measured conductance. Several methods have been developed to estimate the contribution from myocardium, and they only determine a single steady state value for the parallel contribution. Besides, myocardium was treated as purely resistive or mainly capacitive when estimating the myocardial contribution. We question these assumptions and propose that the myocardium is both resistive and capacitive, and its contribution changes during a single cardiac cycle. In vivo magnitude and phase experiments were performed in mice to confirm this hypothesis.

AB - Cardiac volume can be estimated by a conductance catheter system. Both blood and myocardium are conductive, but only the blood conductance is desired. Therefore, the parallel myocardium contribution should be removed from the total measured conductance. Several methods have been developed to estimate the contribution from myocardium, and they only determine a single steady state value for the parallel contribution. Besides, myocardium was treated as purely resistive or mainly capacitive when estimating the myocardial contribution. We question these assumptions and propose that the myocardium is both resistive and capacitive, and its contribution changes during a single cardiac cycle. In vivo magnitude and phase experiments were performed in mice to confirm this hypothesis.

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