Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Ken Ichi Ohba; Masashi Mizokami; Johnson Y.N. Lau; Etsuro Orito; Kazuho Ikeo; Takashi Gojobori

doi:10.1016/0014-5793(95)01441-1

Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Ken Ichi Ohba
, Masashi Mizokami
, Johnson Y.N. Lau
, Etsuro Orito
, Kazuho Ikeo
, Takashi Gojobori

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

88 Citations (Scopus)

Abstract

Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.

Original language	English
Pages (from-to)	232-234
Number of pages	3
Journal	FEBS Letters
Volume	378
Issue number	3
DOIs	https://doi.org/10.1016/0014-5793(95)01441-1
Publication status	Published - 1996 Jan 15

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(95)01441-1

Cite this

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abstract = "Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.",

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AU - Ohba, Ken Ichi

AU - Mizokami, Masashi

AU - Lau, Johnson Y.N.

AU - Orito, Etsuro

AU - Ikeo, Kazuho

AU - Gojobori, Takashi

PY - 1996/1/15

Y1 - 1996/1/15

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AB - Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.

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Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Abstract

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