Expression pattern of nuclear p53 is unique in COS-1 cells

Jenq-Chang Lee, Tsan Shen Lee, Hung Yiu Ho, Hsiao Chiang Hsueh, Wei Tai Huang, Yueh-Ren Ho, Ming-Derg Lai

Research output: Contribution to journalArticle

Abstract

As p53 is transcriptionally inactive in COS-1 cells, we felt it would be interesting to study the relative time course of expression of nuclear p53 and the onset of S phase. Our results indicated that the expression of nuclear p53 lagged behind the onset of S phase in COS-1 cells. In addition, rapid nuclear expression of p53, probably resulting from nuclear translocation, occurred immediately after the addition of serum into COS1 cells. No such phenomena were found in B104-1 and BHK cells.

Original languageEnglish
Pages (from-to)2705-2708
Number of pages4
JournalAnticancer research
Volume16
Issue number5 A
Publication statusPublished - 1996 Sep 1

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COS Cells
S Phase
Serum

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Lee, J-C., Lee, T. S., Ho, H. Y., Hsueh, H. C., Huang, W. T., Ho, Y-R., & Lai, M-D. (1996). Expression pattern of nuclear p53 is unique in COS-1 cells. Anticancer research, 16(5 A), 2705-2708.
Lee, Jenq-Chang ; Lee, Tsan Shen ; Ho, Hung Yiu ; Hsueh, Hsiao Chiang ; Huang, Wei Tai ; Ho, Yueh-Ren ; Lai, Ming-Derg. / Expression pattern of nuclear p53 is unique in COS-1 cells. In: Anticancer research. 1996 ; Vol. 16, No. 5 A. pp. 2705-2708.
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Lee, J-C, Lee, TS, Ho, HY, Hsueh, HC, Huang, WT, Ho, Y-R & Lai, M-D 1996, 'Expression pattern of nuclear p53 is unique in COS-1 cells', Anticancer research, vol. 16, no. 5 A, pp. 2705-2708.

Expression pattern of nuclear p53 is unique in COS-1 cells. / Lee, Jenq-Chang; Lee, Tsan Shen; Ho, Hung Yiu; Hsueh, Hsiao Chiang; Huang, Wei Tai; Ho, Yueh-Ren; Lai, Ming-Derg.

In: Anticancer research, Vol. 16, No. 5 A, 01.09.1996, p. 2705-2708.

Research output: Contribution to journalArticle

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Lee J-C, Lee TS, Ho HY, Hsueh HC, Huang WT, Ho Y-R et al. Expression pattern of nuclear p53 is unique in COS-1 cells. Anticancer research. 1996 Sep 1;16(5 A):2705-2708.