TY - JOUR
T1 - Extensibility effect of poly(3-hexylthiophene) on the glucose sensing performance of mixed poly(3-hexylthiophene)/octadecylamine/glucose oxidase Langmuir-Blodgett films
AU - Wang, Ke Hsuan
AU - Hsu, Wen Ping
AU - Chen, Liang Huei
AU - Lin, Wei Don
AU - Lee, Yuh Lang
N1 - Funding Information:
The financial support for this research by the Ministry of Science and Technology of Taiwan (NSC-104-2221-E-006-143-MY3) is gratefully acknowledged. This research was also supported in part by the Headquarters of University Advancement at the National Cheng Kung University, which is sponsored by the Ministry of Education, Taiwan.
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Poly(3-hexylthiophene) (P3HT) is utilized as a material to enhance the glucose sensing performance of glucose oxidase (GOx) Langmuir-Blodgett (LB) films. To enhance the extensibility and homogeneity of the P3HT in the LB films, octadecylamine (ODA) is introduced. The characteristics of the mixed P3HT/ODA Langmuir monolayers are investigated first and then, utilized as template layers to adsorb GOx from the subphase, preparing P3HT/ODA/GOx Langmuir-Blodgett films for glucose sensing. The results show that P3HT molecules tend to aggregate at the air/liquid interface and, furthermore, the P3HT monolayer has a weak ability to adsorb GOx from the subphase. By using mixed P3HT/ODA monolayer, the presence of ODA not only inhibits the aggregation of P3HT, but also increases the adsorption ability of the monolayer to GOx. The extensibility of P3HT and the homogeneity of the P3HT/ODA monolayers are closely related to the concentration of P3HT/ODA stock solutions. On the glucose sensing experiments, the performance of the P3HT/ODA/GOx LB film is greatly improved due to the presence of P3HT and, furthermore, the sensibility increases with increasing extensibility of P3HT molecules. The best sensitivity achieved for the P3HT/ODA/GOx film is 5.4 μA mM−1 cm−2 which is over two times the value obtained by the ODA/GOx film (2.3 μA mM−1 cm−2).
AB - Poly(3-hexylthiophene) (P3HT) is utilized as a material to enhance the glucose sensing performance of glucose oxidase (GOx) Langmuir-Blodgett (LB) films. To enhance the extensibility and homogeneity of the P3HT in the LB films, octadecylamine (ODA) is introduced. The characteristics of the mixed P3HT/ODA Langmuir monolayers are investigated first and then, utilized as template layers to adsorb GOx from the subphase, preparing P3HT/ODA/GOx Langmuir-Blodgett films for glucose sensing. The results show that P3HT molecules tend to aggregate at the air/liquid interface and, furthermore, the P3HT monolayer has a weak ability to adsorb GOx from the subphase. By using mixed P3HT/ODA monolayer, the presence of ODA not only inhibits the aggregation of P3HT, but also increases the adsorption ability of the monolayer to GOx. The extensibility of P3HT and the homogeneity of the P3HT/ODA monolayers are closely related to the concentration of P3HT/ODA stock solutions. On the glucose sensing experiments, the performance of the P3HT/ODA/GOx LB film is greatly improved due to the presence of P3HT and, furthermore, the sensibility increases with increasing extensibility of P3HT molecules. The best sensitivity achieved for the P3HT/ODA/GOx film is 5.4 μA mM−1 cm−2 which is over two times the value obtained by the ODA/GOx film (2.3 μA mM−1 cm−2).
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U2 - 10.1016/j.colsurfb.2017.04.006
DO - 10.1016/j.colsurfb.2017.04.006
M3 - Article
C2 - 28411475
AN - SCOPUS:85017390856
VL - 155
SP - 104
EP - 110
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
SN - 0927-7765
ER -