Extreme hypergastrinemia caused by atrophic gastritis and Helicobacter pylori infection - A case report

Shih-Ming Huang, Hsienhong Lin Hans Hsienhong Lin, Yeng Wen Trung Yeng Wen, Y. H. Hsu

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We present a case with extremely high serum gastrin induced by atrophic gastritis and Helicobacter pylori infection. The patient, a 95-year-old male, was diagnosed with idiopathic chronic diarrhea. During diagnostic work-up, his fasting serum gastrin was up to 2078pg/mL. The secretin test was negative for gastrinoma. Octreotide scan showed no suspicious lesion except for diffuse faint uptake over the gastric antrum on the 48-hour-delay film. Gastric acidity test revealed achlorhydria. On histology examination, atrophic gastritis with Helicobacter pylori infection was found in the gastric body, but the antral mucus was normal with a slight increase in gastrin-secreting cells. To our knowledge, such extremely high serum gastrin induced by atrophic gastritis and Helicobacter pylori infection has never been reported before.

Original languageEnglish
Pages (from-to)1215-1216
Number of pages2
JournalHepato-Gastroenterology
Volume48
Issue number40
Publication statusPublished - 2001 Aug 29

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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