Due to dramatic progress in microfluidic devices and their applications, the development of microfluidic systems become more and more pertinent in recent years, such as fluidic activation devices, micro-sensors and micro-pumps. In this research, micro-electro-mechanical fabrication technologies are employed to fabricate an innovative valve-less micro-pump under magnetic control. The micro-coil is fabricated by electroforming and utilized to generate control force. Prior to fabrication of micro-pump, commercial software CFD-RC and ANSOFT are used first to simulate the performance of the designed micro-pump. CFD-RC is to observe the flow field and pressure in the micro-channel, and ANSOFT to evaluate if the magnetic force is sufficient enough to activate the membrane of the micro-pump. Finally, the micro-pump is equipped with a personal computer, in which dSPACE simulation module DS1104 is embedded, to realize the closed-loop micro-system.