Fabrication and flow test of long-term hydrophilic fluidic chip without using any surface modification treatment

Chen-Kuei Chung, Y. S. Chen, T. R. Shih

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In order to effectively pump liquid in a fluidic chip, the PDMS or SU8 channels were frequently modified by surface treatments to obtain the hydrophilic surface but encountered the problem of the hydrophobic recovery. In this article, long-term highly hydrophilic fluidic chips were demonstrated using rapid fabrication of low-power CO2 laser ablation and low-temperature glass bonding with an interlayer of liquid crystal polymer (LCP). The intrinsic hydrophilic materials of glass and LCP were beneficial for self-driven flow in the long-term fluidic chip by surface-tension force with no extra fluidic pumps. The higher viscosity fluid could increase the difficulty of self-driven capability. The stability of contact angle and flow test of the chip after 2 months is similar to that at beginning. The high-viscosity human whole blood was successfully driven at an average moving velocity of about 1.89 mm/s for the beginning and at 2.04 mm/s after 2 months. Our fluidic chip simplifies the traditional complex fabrication procedure of glass chips and conquers the problem of traditional hydrophobic recovery.

Original languageEnglish
Pages (from-to)853-857
Number of pages5
JournalMicrofluidics and Nanofluidics
Volume6
Issue number6
DOIs
Publication statusPublished - 2009 Jan 1

Fingerprint

fluidics
Fluidics
Surface treatment
chips
Fabrication
fabrication
Liquid crystal polymers
Glass bonding
glass
Pumps
Viscosity
Recovery
Glass
recovery
liquid crystals
viscosity
pumps
Laser ablation
polymers
Contact angle

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Materials Chemistry

Cite this

@article{ddcb947b033c470291fd6160f37a3f62,
title = "Fabrication and flow test of long-term hydrophilic fluidic chip without using any surface modification treatment",
abstract = "In order to effectively pump liquid in a fluidic chip, the PDMS or SU8 channels were frequently modified by surface treatments to obtain the hydrophilic surface but encountered the problem of the hydrophobic recovery. In this article, long-term highly hydrophilic fluidic chips were demonstrated using rapid fabrication of low-power CO2 laser ablation and low-temperature glass bonding with an interlayer of liquid crystal polymer (LCP). The intrinsic hydrophilic materials of glass and LCP were beneficial for self-driven flow in the long-term fluidic chip by surface-tension force with no extra fluidic pumps. The higher viscosity fluid could increase the difficulty of self-driven capability. The stability of contact angle and flow test of the chip after 2 months is similar to that at beginning. The high-viscosity human whole blood was successfully driven at an average moving velocity of about 1.89 mm/s for the beginning and at 2.04 mm/s after 2 months. Our fluidic chip simplifies the traditional complex fabrication procedure of glass chips and conquers the problem of traditional hydrophobic recovery.",
author = "Chen-Kuei Chung and Chen, {Y. S.} and Shih, {T. R.}",
year = "2009",
month = "1",
day = "1",
doi = "10.1007/s10404-008-0363-8",
language = "English",
volume = "6",
pages = "853--857",
journal = "Microfluidics and Nanofluidics",
issn = "1613-4982",
publisher = "Springer Verlag",
number = "6",

}

Fabrication and flow test of long-term hydrophilic fluidic chip without using any surface modification treatment. / Chung, Chen-Kuei; Chen, Y. S.; Shih, T. R.

In: Microfluidics and Nanofluidics, Vol. 6, No. 6, 01.01.2009, p. 853-857.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fabrication and flow test of long-term hydrophilic fluidic chip without using any surface modification treatment

AU - Chung, Chen-Kuei

AU - Chen, Y. S.

AU - Shih, T. R.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - In order to effectively pump liquid in a fluidic chip, the PDMS or SU8 channels were frequently modified by surface treatments to obtain the hydrophilic surface but encountered the problem of the hydrophobic recovery. In this article, long-term highly hydrophilic fluidic chips were demonstrated using rapid fabrication of low-power CO2 laser ablation and low-temperature glass bonding with an interlayer of liquid crystal polymer (LCP). The intrinsic hydrophilic materials of glass and LCP were beneficial for self-driven flow in the long-term fluidic chip by surface-tension force with no extra fluidic pumps. The higher viscosity fluid could increase the difficulty of self-driven capability. The stability of contact angle and flow test of the chip after 2 months is similar to that at beginning. The high-viscosity human whole blood was successfully driven at an average moving velocity of about 1.89 mm/s for the beginning and at 2.04 mm/s after 2 months. Our fluidic chip simplifies the traditional complex fabrication procedure of glass chips and conquers the problem of traditional hydrophobic recovery.

AB - In order to effectively pump liquid in a fluidic chip, the PDMS or SU8 channels were frequently modified by surface treatments to obtain the hydrophilic surface but encountered the problem of the hydrophobic recovery. In this article, long-term highly hydrophilic fluidic chips were demonstrated using rapid fabrication of low-power CO2 laser ablation and low-temperature glass bonding with an interlayer of liquid crystal polymer (LCP). The intrinsic hydrophilic materials of glass and LCP were beneficial for self-driven flow in the long-term fluidic chip by surface-tension force with no extra fluidic pumps. The higher viscosity fluid could increase the difficulty of self-driven capability. The stability of contact angle and flow test of the chip after 2 months is similar to that at beginning. The high-viscosity human whole blood was successfully driven at an average moving velocity of about 1.89 mm/s for the beginning and at 2.04 mm/s after 2 months. Our fluidic chip simplifies the traditional complex fabrication procedure of glass chips and conquers the problem of traditional hydrophobic recovery.

UR - http://www.scopus.com/inward/record.url?scp=67349223275&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67349223275&partnerID=8YFLogxK

U2 - 10.1007/s10404-008-0363-8

DO - 10.1007/s10404-008-0363-8

M3 - Article

VL - 6

SP - 853

EP - 857

JO - Microfluidics and Nanofluidics

JF - Microfluidics and Nanofluidics

SN - 1613-4982

IS - 6

ER -