Fabrication of hourglass-shaped microaperture via two-stage laser pulses and its application

Chang Yu Chen; Ting Yuan Tu; De Shien Jong; Andrew M. Wo

Fabrication of hourglass-shaped microaperture via two-stage laser pulses and its application

Chang Yu Chen, Ting Yuan Tu, De Shien Jong, Andrew M. Wo

Department of Biomedical Engineering

Research output: Contribution to conference › Paper › peer-review

Abstract

This work presents the fabrication of hourglass-shaped aperture by applying twostage CO₂ laser pulses on glass substrate to control the size of the aperture to 1- 10μm, and applies the fabricated aperture to measure ion-channel activities and to trap single cells in array configuration. First stage laser pulses with longer duration was utilized to generate apertures larger than 10μm, and a series of shorter duration laser pulses was added for maintaining the glass reflow to reduce its diameter. This easy fabrication procedure can be operated without complicated micro-fabrication process for applications of single-cell analysis.

Original language	English
Pages	1648-1650
Number of pages	3
Publication status	Published - 2008 Jan 1
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16

Other

Other	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country	United States
City	San Diego, CA
Period	08-10-12 → 08-10-16

All Science Journal Classification (ASJC) codes

Chemical Engineering (miscellaneous)
Bioengineering

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@conference{e62f68d304bc466795c58149390383bc,

title = "Fabrication of hourglass-shaped microaperture via two-stage laser pulses and its application",

abstract = "This work presents the fabrication of hourglass-shaped aperture by applying twostage CO2 laser pulses on glass substrate to control the size of the aperture to 1- 10μm, and applies the fabricated aperture to measure ion-channel activities and to trap single cells in array configuration. First stage laser pulses with longer duration was utilized to generate apertures larger than 10μm, and a series of shorter duration laser pulses was added for maintaining the glass reflow to reduce its diameter. This easy fabrication procedure can be operated without complicated micro-fabrication process for applications of single-cell analysis.",

author = "Chen, {Chang Yu} and Tu, {Ting Yuan} and Jong, {De Shien} and Wo, {Andrew M.}",

year = "2008",

month = jan,

day = "1",

language = "English",

pages = "1648--1650",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

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Fabrication of hourglass-shaped microaperture via two-stage laser pulses and its application. / Chen, Chang Yu; Tu, Ting Yuan; Jong, De Shien; Wo, Andrew M.

2008. 1648-1650 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Fabrication of hourglass-shaped microaperture via two-stage laser pulses and its application

AU - Chen, Chang Yu

AU - Tu, Ting Yuan

AU - Jong, De Shien

AU - Wo, Andrew M.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - This work presents the fabrication of hourglass-shaped aperture by applying twostage CO2 laser pulses on glass substrate to control the size of the aperture to 1- 10μm, and applies the fabricated aperture to measure ion-channel activities and to trap single cells in array configuration. First stage laser pulses with longer duration was utilized to generate apertures larger than 10μm, and a series of shorter duration laser pulses was added for maintaining the glass reflow to reduce its diameter. This easy fabrication procedure can be operated without complicated micro-fabrication process for applications of single-cell analysis.

AB - This work presents the fabrication of hourglass-shaped aperture by applying twostage CO2 laser pulses on glass substrate to control the size of the aperture to 1- 10μm, and applies the fabricated aperture to measure ion-channel activities and to trap single cells in array configuration. First stage laser pulses with longer duration was utilized to generate apertures larger than 10μm, and a series of shorter duration laser pulses was added for maintaining the glass reflow to reduce its diameter. This easy fabrication procedure can be operated without complicated micro-fabrication process for applications of single-cell analysis.

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Y2 - 12 October 2008 through 16 October 2008

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