Abstract
This work presents the fabrication of hourglass-shaped aperture by applying twostage CO2 laser pulses on glass substrate to control the size of the aperture to 1- 10μm, and applies the fabricated aperture to measure ion-channel activities and to trap single cells in array configuration. First stage laser pulses with longer duration was utilized to generate apertures larger than 10μm, and a series of shorter duration laser pulses was added for maintaining the glass reflow to reduce its diameter. This easy fabrication procedure can be operated without complicated micro-fabrication process for applications of single-cell analysis.
Original language | English |
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Pages | 1648-1650 |
Number of pages | 3 |
Publication status | Published - 2008 Jan 1 |
Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16 |
Other
Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
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Country/Territory | United States |
City | San Diego, CA |
Period | 08-10-12 → 08-10-16 |
All Science Journal Classification (ASJC) codes
- Chemical Engineering (miscellaneous)
- Bioengineering