Fabrication of microfluidic chip using foil-assisted CO2 laser ablation for suspended particles separation

H. P. Long, C. C. Lai, C. K. Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Lab on a chip was mainly used in the simplification of biomedical detection step and separation was one of the indispensable pretreatment during the detection process. In this study, a combination channel of spiral and backward facing step patterns were designed to optimize the separation function without any extra power like electric or magnetic field. The foil-assisted CO2 laser method was used to fabricate a spiral microfluidic chip with polymethylmethacrylate polymer for the master of suspended particles separation. The laser ablation generated poor surfaces quality with bulge and scorches can be diminished using foil-assisted laser micromachining technique. The low-cost and time-saving procedure, including microchip fabrication and surface modification, has been developed to apply positively in microfluidic separation chip based on the flow distribution design of spiral dean vortices and backward facing step, which can provide 99% separation efficiency within a certain flow range.

Original languageEnglish
Title of host publication2015 IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages259-262
Number of pages4
ISBN (Electronic)9781467366953
DOIs
Publication statusPublished - 2015 Jul 1
Event10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015 - Xi'an, China
Duration: 2015 Apr 72015 Apr 11

Publication series

Name2015 IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015

Other

Other10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015
CountryChina
CityXi'an
Period15-04-0715-04-11

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Electrical and Electronic Engineering
  • Hardware and Architecture

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