Facile preparation of self-assembled hydrogel-like GdPO4· H2O nanorods

Chih-Chia Huang, Yi Wei Lo, Wen Shuo Kuo, Jih Ru Hwu, Wu-Chou Su, Dar-Bin Shieh, Chen-Sheng Yeh

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Of the methods employed in the preparation of one-dimensional lanthanide phosphate (LnPO4) nanorods/nanowires, such as GdPO4, the hydrothermal method has been mainly used as a synthetic route. In this study, we report a facile low-temperature solution approach to prepare GdPO4 · H2O nanorods by simply refluxing GdCl3 and KH2PO4 for only 15 min at 88°C, an approach that can easily be scaled up by increasing the reagent amounts. We observed a highly viscous macroscopic hydrogel-like material when we mixed as-prepared GdPO 4 ·H2O nanomaterials with H2O. Hydrogels are an important class of biomaterials. Their building blocks, normally formed from protein-, peptide-, polymer-, and lipid-based materials, offer three-dimensional scaffolds for drug delivery, tissue engineering, and biosensors. Our preliminary results showed that GdPO4·H 2O hydrogels could be used for encapsulation and drug release, and that they were biocompatible, acting as scaffolds to foster cell proliferation. These findings suggested that they might have biomedical uses. Our findings may lead to the creation of other inorganic nanomaterial-based hydrogels apart from the organic and biomolecular protein-, peptide-, polymer-, and lipid-based building blocks.

Original languageEnglish
Pages (from-to)8309-8313
Number of pages5
JournalLangmuir
Volume24
Issue number15
DOIs
Publication statusPublished - 2008 Aug 5

Fingerprint

Hydrogels
Hydrogel
Nanorods
nanorods
peptides
lipids
drugs
Scaffolds (biology)
proteins
Nanostructured materials
preparation
tissue engineering
Polymers
polymers
bioinstrumentation
Lipids
Peptides
reagents
delivery
phosphates

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

Cite this

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title = "Facile preparation of self-assembled hydrogel-like GdPO4· H2O nanorods",
abstract = "Of the methods employed in the preparation of one-dimensional lanthanide phosphate (LnPO4) nanorods/nanowires, such as GdPO4, the hydrothermal method has been mainly used as a synthetic route. In this study, we report a facile low-temperature solution approach to prepare GdPO4 · H2O nanorods by simply refluxing GdCl3 and KH2PO4 for only 15 min at 88°C, an approach that can easily be scaled up by increasing the reagent amounts. We observed a highly viscous macroscopic hydrogel-like material when we mixed as-prepared GdPO 4 ·H2O nanomaterials with H2O. Hydrogels are an important class of biomaterials. Their building blocks, normally formed from protein-, peptide-, polymer-, and lipid-based materials, offer three-dimensional scaffolds for drug delivery, tissue engineering, and biosensors. Our preliminary results showed that GdPO4·H 2O hydrogels could be used for encapsulation and drug release, and that they were biocompatible, acting as scaffolds to foster cell proliferation. These findings suggested that they might have biomedical uses. Our findings may lead to the creation of other inorganic nanomaterial-based hydrogels apart from the organic and biomolecular protein-, peptide-, polymer-, and lipid-based building blocks.",
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Facile preparation of self-assembled hydrogel-like GdPO4· H2O nanorods. / Huang, Chih-Chia; Lo, Yi Wei; Kuo, Wen Shuo; Hwu, Jih Ru; Su, Wu-Chou; Shieh, Dar-Bin; Yeh, Chen-Sheng.

In: Langmuir, Vol. 24, No. 15, 05.08.2008, p. 8309-8313.

Research output: Contribution to journalArticle

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AU - Huang, Chih-Chia

AU - Lo, Yi Wei

AU - Kuo, Wen Shuo

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AU - Su, Wu-Chou

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AU - Yeh, Chen-Sheng

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