Facile preparation of self-assembled hydrogel-like GdPO4· H2O nanorods

Chih Chia Huang, Yi Wei Lo, Wen Shuo Kuo, Jih Ru Hwu, Wu Chou Su, Dar Bin Shieh, Chen Sheng Yeh

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Of the methods employed in the preparation of one-dimensional lanthanide phosphate (LnPO4) nanorods/nanowires, such as GdPO4, the hydrothermal method has been mainly used as a synthetic route. In this study, we report a facile low-temperature solution approach to prepare GdPO4 · H2O nanorods by simply refluxing GdCl3 and KH2PO4 for only 15 min at 88°C, an approach that can easily be scaled up by increasing the reagent amounts. We observed a highly viscous macroscopic hydrogel-like material when we mixed as-prepared GdPO 4 ·H2O nanomaterials with H2O. Hydrogels are an important class of biomaterials. Their building blocks, normally formed from protein-, peptide-, polymer-, and lipid-based materials, offer three-dimensional scaffolds for drug delivery, tissue engineering, and biosensors. Our preliminary results showed that GdPO4·H 2O hydrogels could be used for encapsulation and drug release, and that they were biocompatible, acting as scaffolds to foster cell proliferation. These findings suggested that they might have biomedical uses. Our findings may lead to the creation of other inorganic nanomaterial-based hydrogels apart from the organic and biomolecular protein-, peptide-, polymer-, and lipid-based building blocks.

Original languageEnglish
Pages (from-to)8309-8313
Number of pages5
Issue number15
Publication statusPublished - 2008 Aug 5

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry


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