Fetal head circumference in normal pregnancy: Remodeling by Altman's method

C. H. Chang, F. M. Chang, C. H. Yu, B. L. Yao, H. C. Ko

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: The purpose of this study was to build a chart of normal fetal head circumference (HC) in the Taiwanese population based on a pure cross-sectional design without the weaknesses common to previously published reports. Materials and Methods: Normal singleton fetuses of between 16 and 41 weeks of gestation were enrolled in this study in the Antenatal Ultrasound Unit of National Cheng Kung University Hospital. Each subject was accepted for only one scan. The data were analyzed by polynomial regression analysis and the best-fit equations for predicting fetal growth were determined. Altman's model was used to calculate the standard deviation for each gestational age (GA) before constructing the charts of fetal growth centiles. Results: A total of 2,025 normal growth fetuses were included in this cross- sectional study. The best-fit equation in the prediction of fetal GA using HC is GA = -5.52053 x 10-3 x HC + 0.02401 x HC2 + 13.69939 (R = 0.97897, p < 0.0001). The best-fit equation in the prediction of fetal HC using GA is HC = -15.00997 + 1.96453 x GA-0.01949 x GA2 (R = 0.98211, p < 0.0001). Tables for HC growth centile charts are generated as a reference for prenatal care. Conclusion: Strict criteria of study design and appropriate statistical modeling have been used in the calculation of our fetal HC values and we believe them to be more accurate than previous studies in assessing fetal head growth in Taiwan.

Original languageEnglish
Pages (from-to)61-67
Number of pages7
JournalJournal of Medical Ultrasound
Volume6
Issue number2
Publication statusPublished - 1998 Jan 1

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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