Formosalides A and B, cytotoxic 17-membered ring macrolides from a marine dinoflagellate Prorocentrum sp.

Chung Kuang Lu; Yi Min Chen; Siang Hang Wang; Ying Yan Wu; Ying Min Cheng

doi:10.1016/j.tetlet.2009.02.013

Formosalides A and B, cytotoxic 17-membered ring macrolides from a marine dinoflagellate Prorocentrum sp.

Chung Kuang Lu, Yi Min Chen, Siang Hang Wang, Ying Yan Wu, Ying Min Cheng

Department of Biotechnology and Bioindustry Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Formosalides A (1) and B (2), two novel cytotoxic 17-membered ring macrolides with all-cis tetraenes, a tetrahydropyran ring, and a tetrahydrofuran ring, were isolated from the cultured marine dinoflagellate Prorocentrum sp. Their gross structures, including local relative stereostructures, were elucidated by extensive spectroscopic studies.

Original language	English
Pages (from-to)	1825-1827
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	16
DOIs	https://doi.org/10.1016/j.tetlet.2009.02.013
Publication status	Published - 2009 Apr 22

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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abstract = "Formosalides A (1) and B (2), two novel cytotoxic 17-membered ring macrolides with all-cis tetraenes, a tetrahydropyran ring, and a tetrahydrofuran ring, were isolated from the cultured marine dinoflagellate Prorocentrum sp. Their gross structures, including local relative stereostructures, were elucidated by extensive spectroscopic studies.",

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AU - Lu, Chung Kuang

AU - Chen, Yi Min

AU - Wang, Siang Hang

AU - Wu, Ying Yan

AU - Cheng, Ying Min

PY - 2009/4/22

Y1 - 2009/4/22

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AB - Formosalides A (1) and B (2), two novel cytotoxic 17-membered ring macrolides with all-cis tetraenes, a tetrahydropyran ring, and a tetrahydrofuran ring, were isolated from the cultured marine dinoflagellate Prorocentrum sp. Their gross structures, including local relative stereostructures, were elucidated by extensive spectroscopic studies.

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