TY - GEN
T1 - FPW biosensor with low insertion loss for detection of Tetrahydrocannabinol antigen
AU - Lan, Je Wei
AU - Huang, I. Yu
AU - Lin, Yu Cheng
AU - Huang, Wen Hui
AU - Yeh, Chia Hsien
AU - Hsieh, Chia Hsu
N1 - Funding Information:
This investigation is partially supported by Ministry of Science and Technology under grant MOST 105-2622-E-006-018-CC2, MOST 105-2218-E-110-006, MOST 105-2221-E-110-080, the authors are also indebted to the National Nano Device Laboratories (NDL) and National Sun Yat-sen University in Taiwan for their assistance in providing access to their processing facilities.
Publisher Copyright:
© 2017 IEEE.
PY - 2017/7/26
Y1 - 2017/7/26
N2 - Conventional flexural plate-wave (FPW) devices usually have high insertion loss, so we designed focus-type interdigital transducers (IDTs) that can effectively constrain launched wave energy, and adopted a focus-type silicon-grooved reflective grating structure (RGS) to reduce wave propagation loss. The results reveal that the proposed FPW devices have lower insertion loss (-38.698 dB). Then, we used the improved FPW device to develop a novel FPW-based biosensor for rapid detection of Tetrahydrocannabinol (THC) concentration in human urine by integrating. This FPW-THC biosensor has low detection limit (40 ng/mL), high sensitivity (126.67 cm2/g), and high sensing linearity (R-square=0.916).
AB - Conventional flexural plate-wave (FPW) devices usually have high insertion loss, so we designed focus-type interdigital transducers (IDTs) that can effectively constrain launched wave energy, and adopted a focus-type silicon-grooved reflective grating structure (RGS) to reduce wave propagation loss. The results reveal that the proposed FPW devices have lower insertion loss (-38.698 dB). Then, we used the improved FPW device to develop a novel FPW-based biosensor for rapid detection of Tetrahydrocannabinol (THC) concentration in human urine by integrating. This FPW-THC biosensor has low detection limit (40 ng/mL), high sensitivity (126.67 cm2/g), and high sensing linearity (R-square=0.916).
UR - https://www.scopus.com/pages/publications/85029369835
UR - https://www.scopus.com/pages/publications/85029369835#tab=citedBy
U2 - 10.1109/TRANSDUCERS.2017.7994368
DO - 10.1109/TRANSDUCERS.2017.7994368
M3 - Conference contribution
AN - SCOPUS:85029369835
T3 - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
SP - 1600
EP - 1603
BT - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017
Y2 - 18 June 2017 through 22 June 2017
ER -