Abstract
The IL-1 receptors are responsible for transmitting signaling in immune responses. Ge et al. investigated the effect of a common D2/D3 linker within IL-1 receptors and revealed the functional role of inherent inter-domain flexibility in ligand recognition and signal transduction.
Original language | English |
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Pages (from-to) | 1296-1307.e5 |
Journal | Structure |
Volume | 27 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2019 Aug 6 |
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All Science Journal Classification (ASJC) codes
- Structural Biology
- Molecular Biology
Cite this
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Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling. / Ge, Jiwan; Remesh, Soumya G.; Hammel, Michal; Pan, Si; Mahan, Andrew D.; Wang, Shu-Ying; Wang, Xinquan.
In: Structure, Vol. 27, No. 8, 06.08.2019, p. 1296-1307.e5.Research output: Contribution to journal › Article
TY - JOUR
T1 - Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling
AU - Ge, Jiwan
AU - Remesh, Soumya G.
AU - Hammel, Michal
AU - Pan, Si
AU - Mahan, Andrew D.
AU - Wang, Shu-Ying
AU - Wang, Xinquan
PY - 2019/8/6
Y1 - 2019/8/6
N2 - The IL-1 receptors are responsible for transmitting signaling in immune responses. Ge et al. investigated the effect of a common D2/D3 linker within IL-1 receptors and revealed the functional role of inherent inter-domain flexibility in ligand recognition and signal transduction.
AB - The IL-1 receptors are responsible for transmitting signaling in immune responses. Ge et al. investigated the effect of a common D2/D3 linker within IL-1 receptors and revealed the functional role of inherent inter-domain flexibility in ligand recognition and signal transduction.
UR - http://www.scopus.com/inward/record.url?scp=85069925222&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85069925222&partnerID=8YFLogxK
U2 - 10.1016/j.str.2019.05.011
DO - 10.1016/j.str.2019.05.011
M3 - Article
C2 - 31257107
AN - SCOPUS:85069925222
VL - 27
SP - 1296-1307.e5
JO - Structure with Folding & design
JF - Structure with Folding & design
SN - 0969-2126
IS - 8
ER -