Abstract
The present invention relates to a new type of functionalized nanoparticles for drug delivery, comprising a type of polymer nanoparticles, a polymer stabilizer coating, and a drug, wherein said polymer stabilizer coating is coated on the surface of said type of polymer nanoparticles, and said drug is conjugated to said polymer stabilizer coating. The present invention also relates to a method for preparing the nanoparticles; and provides a method for treating an ischemic or degenerative disease, comprising administrating an effective amount of the type of functionalized nanoparticles to a subject.
| Translated title of the contribution | 可延長IGF-1釋放以保護心肌的PLGA奈米粒子 |
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| Original language | English |
| Patent number | 9198873 |
| Publication status | Published - 2012 Jan 19 |