Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33T with its coral host

Jiun Yan Ding, Jia Ho Shiu, Wen Ming Chen, Yin Ru Chiang, Sen Lin Tang

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The bacterial genus Endozoicomonas was commonly detected in healthy corals in many coral-associated bacteria studies in the past decade. Although, it is likely to be a core member of coral microbiota, little is known about its ecological roles. To decipher potential interactions between bacteria and their coral hosts, we sequenced and investigated the first culturable endozoicomonal bacterium from coral, the E. montiporae CL-33T. Its genome had potential sign of ongoing genome erosion and gene exchange with its host. Testosterone degradation and type III secretion system are commonly present in Endozoicomonas and may have roles to recognize and deliver effectors to their hosts. Moreover, genes of eukaryotic ephrin ligand B2 are present in its genome; presumably, this bacterium could move into coral cells via endocytosis after binding to coral's Eph receptors. In addition, 7,8-dihydro-8-oxoguanine triphosphatase and isocitrate lyase are possible type III secretion effectors that might help coral to prevent mitochondrial dysfunction and promote gluconeogenesis, especially under stress conditions. Based on all these findings, we inferred that E. montiporae was a facultative endosymbiont that can recognize, translocate, communicate and modulate its coral host.

Original languageEnglish
Article number251
JournalFrontiers in Microbiology
Volume7
Issue numberMAR
DOIs
Publication statusPublished - 2016 Mar 8

Fingerprint

Anthozoa
Bacteria
Genome
Ephrin-B2
Isocitrate Lyase
Eph Family Receptors
Gluconeogenesis
Microbiota
Endocytosis
Genes
Testosterone
Ligands

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)

Cite this

Ding, Jiun Yan ; Shiu, Jia Ho ; Chen, Wen Ming ; Chiang, Yin Ru ; Tang, Sen Lin. / Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33T with its coral host. In: Frontiers in Microbiology. 2016 ; Vol. 7, No. MAR.
@article{dbac748c8e694dfd8ceab454d30ffc5c,
title = "Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33T with its coral host",
abstract = "The bacterial genus Endozoicomonas was commonly detected in healthy corals in many coral-associated bacteria studies in the past decade. Although, it is likely to be a core member of coral microbiota, little is known about its ecological roles. To decipher potential interactions between bacteria and their coral hosts, we sequenced and investigated the first culturable endozoicomonal bacterium from coral, the E. montiporae CL-33T. Its genome had potential sign of ongoing genome erosion and gene exchange with its host. Testosterone degradation and type III secretion system are commonly present in Endozoicomonas and may have roles to recognize and deliver effectors to their hosts. Moreover, genes of eukaryotic ephrin ligand B2 are present in its genome; presumably, this bacterium could move into coral cells via endocytosis after binding to coral's Eph receptors. In addition, 7,8-dihydro-8-oxoguanine triphosphatase and isocitrate lyase are possible type III secretion effectors that might help coral to prevent mitochondrial dysfunction and promote gluconeogenesis, especially under stress conditions. Based on all these findings, we inferred that E. montiporae was a facultative endosymbiont that can recognize, translocate, communicate and modulate its coral host.",
author = "Ding, {Jiun Yan} and Shiu, {Jia Ho} and Chen, {Wen Ming} and Chiang, {Yin Ru} and Tang, {Sen Lin}",
year = "2016",
month = "3",
day = "8",
doi = "10.3389/fmicb.2016.00251",
language = "English",
volume = "7",
journal = "Frontiers in Microbiology",
issn = "1664-302X",
publisher = "Frontiers Media S. A.",
number = "MAR",

}

Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33T with its coral host. / Ding, Jiun Yan; Shiu, Jia Ho; Chen, Wen Ming; Chiang, Yin Ru; Tang, Sen Lin.

In: Frontiers in Microbiology, Vol. 7, No. MAR, 251, 08.03.2016.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33T with its coral host

AU - Ding, Jiun Yan

AU - Shiu, Jia Ho

AU - Chen, Wen Ming

AU - Chiang, Yin Ru

AU - Tang, Sen Lin

PY - 2016/3/8

Y1 - 2016/3/8

N2 - The bacterial genus Endozoicomonas was commonly detected in healthy corals in many coral-associated bacteria studies in the past decade. Although, it is likely to be a core member of coral microbiota, little is known about its ecological roles. To decipher potential interactions between bacteria and their coral hosts, we sequenced and investigated the first culturable endozoicomonal bacterium from coral, the E. montiporae CL-33T. Its genome had potential sign of ongoing genome erosion and gene exchange with its host. Testosterone degradation and type III secretion system are commonly present in Endozoicomonas and may have roles to recognize and deliver effectors to their hosts. Moreover, genes of eukaryotic ephrin ligand B2 are present in its genome; presumably, this bacterium could move into coral cells via endocytosis after binding to coral's Eph receptors. In addition, 7,8-dihydro-8-oxoguanine triphosphatase and isocitrate lyase are possible type III secretion effectors that might help coral to prevent mitochondrial dysfunction and promote gluconeogenesis, especially under stress conditions. Based on all these findings, we inferred that E. montiporae was a facultative endosymbiont that can recognize, translocate, communicate and modulate its coral host.

AB - The bacterial genus Endozoicomonas was commonly detected in healthy corals in many coral-associated bacteria studies in the past decade. Although, it is likely to be a core member of coral microbiota, little is known about its ecological roles. To decipher potential interactions between bacteria and their coral hosts, we sequenced and investigated the first culturable endozoicomonal bacterium from coral, the E. montiporae CL-33T. Its genome had potential sign of ongoing genome erosion and gene exchange with its host. Testosterone degradation and type III secretion system are commonly present in Endozoicomonas and may have roles to recognize and deliver effectors to their hosts. Moreover, genes of eukaryotic ephrin ligand B2 are present in its genome; presumably, this bacterium could move into coral cells via endocytosis after binding to coral's Eph receptors. In addition, 7,8-dihydro-8-oxoguanine triphosphatase and isocitrate lyase are possible type III secretion effectors that might help coral to prevent mitochondrial dysfunction and promote gluconeogenesis, especially under stress conditions. Based on all these findings, we inferred that E. montiporae was a facultative endosymbiont that can recognize, translocate, communicate and modulate its coral host.

UR - http://www.scopus.com/inward/record.url?scp=84964389035&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964389035&partnerID=8YFLogxK

U2 - 10.3389/fmicb.2016.00251

DO - 10.3389/fmicb.2016.00251

M3 - Article

AN - SCOPUS:84964389035

VL - 7

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

SN - 1664-302X

IS - MAR

M1 - 251

ER -