Hemodynamic effects of endoleak formation in abdominal aortic aneurysm patients with stent-graft implants

Yueh Hsun Lu, Chia-Yuan Chen, Prahlad G. Menon, Kuan Ting Liu, Hsing Hung Lin

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Endoleaks may evolve and become severe post-surgical complications in patients with abdominal aortic aneurysms (AAAs). After endovascular aortic aneurysm repair (EVAR), endoleaks may induce EVAR failure. Therefore, the early detection and management of endoleak development could help reduce the need for reoperation. An endoleak is characterized by blood flow that leaks into the cavity between the stent-graft (SG) and aneurysm sac. Comprehensive hemodynamic analysis can identify the relationship of flow-induced wall stress and endoleak formation. Given this hypothesis, a numerical analysis of fluid-structure interaction was performed in this study. SG geometry and AAA flow dynamics were incorporated using the physiological conditions of three patient-specific models of AAA after EVAR. Endoleak locations were well matched to the local peak locations of von Mises stress in the aneurysm bulges of these patients. Further investigation on the associated blood flow structures could provide insights on the physical relationship between hemodynamic force and endoleak formation. The presented analytical procedure offers a reliable alternative for endoleak prediction and detection. This method may be used for post-EVAR patient care with sophisticated imaging techniques such as magnetic resonance, computed tomography, and digital subtraction angiography.

Original languageEnglish
Pages (from-to)554-558
Number of pages5
JournalJournal of Medical and Biological Engineering
Volume34
Issue number6
DOIs
Publication statusPublished - 2014 Jan 1

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Endoleak
Stents
Abdominal Aortic Aneurysm
Hemodynamics
Grafts
Repair
Transplants
Aortic Aneurysm
Blood
Angiography
Fluid structure interaction
Magnetic resonance
Flow structure
Aneurysm
Tomography
Numerical analysis
Imaging techniques
Digital Subtraction Angiography
Geometry
Reoperation

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Medicine(all)

Cite this

Lu, Yueh Hsun ; Chen, Chia-Yuan ; Menon, Prahlad G. ; Liu, Kuan Ting ; Lin, Hsing Hung. / Hemodynamic effects of endoleak formation in abdominal aortic aneurysm patients with stent-graft implants. In: Journal of Medical and Biological Engineering. 2014 ; Vol. 34, No. 6. pp. 554-558.
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Hemodynamic effects of endoleak formation in abdominal aortic aneurysm patients with stent-graft implants. / Lu, Yueh Hsun; Chen, Chia-Yuan; Menon, Prahlad G.; Liu, Kuan Ting; Lin, Hsing Hung.

In: Journal of Medical and Biological Engineering, Vol. 34, No. 6, 01.01.2014, p. 554-558.

Research output: Contribution to journalArticle

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