Heterogeneity of multiple-pore membranes investigated with ion conductance microscopy

Yi Zhou, Chiao Chen Chen, Lane A. Baker

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)


Heterogeneous conductance of individual pores on a porous membrane was studied with a four-electrode scanning ion conductance microscope (SICM). Application of a potential difference across the membrane resulted in migration of ions through nanopores, where subsequent conductance changes were measured by a nanopipet positioned above the nanopore as a change in pipet current. Current responses of single-pore membranes and individual pores within a multipore membrane were examined and demonstrated variations in ion current rectification (ICR) ratios due to the small differences in pore geometries.

Original languageEnglish
Pages (from-to)3003-3009
Number of pages7
JournalAnalytical Chemistry
Issue number6
Publication statusPublished - 2012 Mar 20

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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