Heterotrophic cultivation of microalgae for pigment production: A review

Jianjun Hu, Dillirani Nagarajan, Quanguo Zhang, Jo-Shu Chang, Duu Jong Lee

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

Pigments (mainly carotenoids) are important nutraceuticals known for their potent anti-oxidant activities and have been used extensively as high end health supplements. Microalgae are the most promising sources of natural carotenoids and are devoid of the toxic effects associated with synthetic derivatives. Compared to photoautotrophic cultivation, heterotrophic cultivation of microalgae in well-controlled bioreactors for pigments production has attracted much attention for commercial applications due to overcoming the difficulties associated with the supply of CO2 and light, as well as avoiding the contamination problems and land requirements in open autotrophic culture systems. In this review, the heterotrophic metabolic potential of microalgae and their uses in pigment production are comprehensively described. Strategies to enhance pigment production under heterotrophic conditions are critically discussed and the challenges faced in heterotrophic pigment production with possible alternative solutions are presented.

Original languageEnglish
Pages (from-to)54-67
Number of pages14
JournalBiotechnology Advances
Volume36
Issue number1
DOIs
Publication statusPublished - 2018 Jan 1

Fingerprint

Microalgae
Pigments
Carotenoids
Poisons
Bioreactors
Dietary Supplements
Oxidants
Light
Health
Contamination
Derivatives

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

Cite this

Hu, Jianjun ; Nagarajan, Dillirani ; Zhang, Quanguo ; Chang, Jo-Shu ; Lee, Duu Jong. / Heterotrophic cultivation of microalgae for pigment production : A review. In: Biotechnology Advances. 2018 ; Vol. 36, No. 1. pp. 54-67.
@article{24d3d3294c1d4a609bb8cb720840b48b,
title = "Heterotrophic cultivation of microalgae for pigment production: A review",
abstract = "Pigments (mainly carotenoids) are important nutraceuticals known for their potent anti-oxidant activities and have been used extensively as high end health supplements. Microalgae are the most promising sources of natural carotenoids and are devoid of the toxic effects associated with synthetic derivatives. Compared to photoautotrophic cultivation, heterotrophic cultivation of microalgae in well-controlled bioreactors for pigments production has attracted much attention for commercial applications due to overcoming the difficulties associated with the supply of CO2 and light, as well as avoiding the contamination problems and land requirements in open autotrophic culture systems. In this review, the heterotrophic metabolic potential of microalgae and their uses in pigment production are comprehensively described. Strategies to enhance pigment production under heterotrophic conditions are critically discussed and the challenges faced in heterotrophic pigment production with possible alternative solutions are presented.",
author = "Jianjun Hu and Dillirani Nagarajan and Quanguo Zhang and Jo-Shu Chang and Lee, {Duu Jong}",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.biotechadv.2017.09.009",
language = "English",
volume = "36",
pages = "54--67",
journal = "Biotechnology Advances",
issn = "0734-9750",
publisher = "Elsevier Inc.",
number = "1",

}

Heterotrophic cultivation of microalgae for pigment production : A review. / Hu, Jianjun; Nagarajan, Dillirani; Zhang, Quanguo; Chang, Jo-Shu; Lee, Duu Jong.

In: Biotechnology Advances, Vol. 36, No. 1, 01.01.2018, p. 54-67.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Heterotrophic cultivation of microalgae for pigment production

T2 - A review

AU - Hu, Jianjun

AU - Nagarajan, Dillirani

AU - Zhang, Quanguo

AU - Chang, Jo-Shu

AU - Lee, Duu Jong

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Pigments (mainly carotenoids) are important nutraceuticals known for their potent anti-oxidant activities and have been used extensively as high end health supplements. Microalgae are the most promising sources of natural carotenoids and are devoid of the toxic effects associated with synthetic derivatives. Compared to photoautotrophic cultivation, heterotrophic cultivation of microalgae in well-controlled bioreactors for pigments production has attracted much attention for commercial applications due to overcoming the difficulties associated with the supply of CO2 and light, as well as avoiding the contamination problems and land requirements in open autotrophic culture systems. In this review, the heterotrophic metabolic potential of microalgae and their uses in pigment production are comprehensively described. Strategies to enhance pigment production under heterotrophic conditions are critically discussed and the challenges faced in heterotrophic pigment production with possible alternative solutions are presented.

AB - Pigments (mainly carotenoids) are important nutraceuticals known for their potent anti-oxidant activities and have been used extensively as high end health supplements. Microalgae are the most promising sources of natural carotenoids and are devoid of the toxic effects associated with synthetic derivatives. Compared to photoautotrophic cultivation, heterotrophic cultivation of microalgae in well-controlled bioreactors for pigments production has attracted much attention for commercial applications due to overcoming the difficulties associated with the supply of CO2 and light, as well as avoiding the contamination problems and land requirements in open autotrophic culture systems. In this review, the heterotrophic metabolic potential of microalgae and their uses in pigment production are comprehensively described. Strategies to enhance pigment production under heterotrophic conditions are critically discussed and the challenges faced in heterotrophic pigment production with possible alternative solutions are presented.

UR - http://www.scopus.com/inward/record.url?scp=85030702241&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030702241&partnerID=8YFLogxK

U2 - 10.1016/j.biotechadv.2017.09.009

DO - 10.1016/j.biotechadv.2017.09.009

M3 - Review article

C2 - 28947090

AN - SCOPUS:85030702241

VL - 36

SP - 54

EP - 67

JO - Biotechnology Advances

JF - Biotechnology Advances

SN - 0734-9750

IS - 1

ER -