TY - JOUR
T1 - High case-fatality rate of adults with dengue hemorrhagic fever during an outbreak in non-endemic Taiwan
T2 - Risk factors for dengue-infected elders
AU - Liu, Ching Chuan
AU - Huang, Kao Jean
AU - Huang, Mei Chih
AU - Lin, J. J.
AU - Wang, S. M.
AU - Liu, Jen Jou
AU - Tsai, Jih Jin
AU - Huang, Jyh Hsiung
AU - Lin, Yee Shin
AU - Liu, Hsiao Sheng
AU - Yeh, Trai Ming
AU - Lei, Huan Yao
PY - 2008
Y1 - 2008
N2 - In 2002, a dengue outbreak occurred in Taiwan with 5336 confirmed cases, 242 DHF and 21 death, the case fatality rate reached 8.7% (21/242). The demographic data of these age-specific dengue patients showed that dengue virus infection caused symptom primarily occurred in adults. A comparative analysis of clinical and laboratory data for DF, DHF/DSS and fatal DSS found that high fatality from dengue infection was associated with the following patient conditions: (1) age above 55 years, (2) underlying diseases with hypertension, chronic renal insufficiency, or diabetes, (3) abnormal thrombocytopenia, APTT and PT prolongation, low hematocrit (<30%) and leukocytosis, (4) abnormal elevation of AST, ALT and BUN. In a non-endemic area like Taiwan, dengue should be considered as an adult infectious disease and the dengue-infected elders will have higher morbidity or mortality.
AB - In 2002, a dengue outbreak occurred in Taiwan with 5336 confirmed cases, 242 DHF and 21 death, the case fatality rate reached 8.7% (21/242). The demographic data of these age-specific dengue patients showed that dengue virus infection caused symptom primarily occurred in adults. A comparative analysis of clinical and laboratory data for DF, DHF/DSS and fatal DSS found that high fatality from dengue infection was associated with the following patient conditions: (1) age above 55 years, (2) underlying diseases with hypertension, chronic renal insufficiency, or diabetes, (3) abnormal thrombocytopenia, APTT and PT prolongation, low hematocrit (<30%) and leukocytosis, (4) abnormal elevation of AST, ALT and BUN. In a non-endemic area like Taiwan, dengue should be considered as an adult infectious disease and the dengue-infected elders will have higher morbidity or mortality.
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U2 - 10.3844/ajidsp.2008.10.17
DO - 10.3844/ajidsp.2008.10.17
M3 - Article
AN - SCOPUS:58449098447
SN - 1553-6203
VL - 4
SP - 10
EP - 17
JO - American Journal of Infectious Diseases
JF - American Journal of Infectious Diseases
IS - 1
ER -