Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

Research output: Contribution to journalLetter

5 Citations (Scopus)

Abstract

In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.

Original languageEnglish
Pages (from-to)524-526
Number of pages3
JournalExperimental Dermatology
Volume26
Issue number6
DOIs
Publication statusPublished - 2017 Jun 1

Fingerprint

Alopecia
Leptin
Plasmas
Androgens
Logistics
Multivariate Analysis
Odds Ratio

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology

Cite this

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title = "Higher plasma leptin is associated with higher risk of androgenetic alopecia in men",
abstract = "In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.",
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Higher plasma leptin is associated with higher risk of androgenetic alopecia in men. / Yang, Chao-Chun; Chung, Pei Lun; Lin, Li Yu; Hughes, Michael Warren; Tsai, Yau-Sheng.

In: Experimental Dermatology, Vol. 26, No. 6, 01.06.2017, p. 524-526.

Research output: Contribution to journalLetter

TY - JOUR

T1 - Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

AU - Yang, Chao-Chun

AU - Chung, Pei Lun

AU - Lin, Li Yu

AU - Hughes, Michael Warren

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AB - In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.

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