Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

Chao Chun Yang; Pei Lun Chung; Li Yu Lin; Michael W. Hughes; Yau Sheng Tsai

doi:10.1111/exd.13369

Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

Chao Chun Yang, Pei Lun Chung, Li Yu Lin, Michael W. Hughes, Yau Sheng Tsai

Research output: Contribution to journal › Letter › peer-review

11 Citations (Scopus)

Abstract

In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.

Original language	English
Pages (from-to)	524-526
Number of pages	3
Journal	Experimental Dermatology
Volume	26
Issue number	6
DOIs	https://doi.org/10.1111/exd.13369
Publication status	Published - 2017 Jun

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Dermatology

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title = "Higher plasma leptin is associated with higher risk of androgenetic alopecia in men",

abstract = "In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.",

author = "Yang, {Chao Chun} and Chung, {Pei Lun} and Lin, {Li Yu} and Hughes, {Michael W.} and Tsai, {Yau Sheng}",

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T1 - Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

AU - Yang, Chao Chun

AU - Chung, Pei Lun

AU - Lin, Li Yu

AU - Hughes, Michael W.

AU - Tsai, Yau Sheng

PY - 2017/6

Y1 - 2017/6

N2 - In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.

AB - In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty-eight subjects were enrolled including 29 AGA and 19 non-AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non-AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.

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JO - Experimental Dermatology

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Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

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