Highly efficient hydrolysis of phosphodiester by a copper(II)-chelated chitosan magnetic nanocarrier

Yang Chuang Chang, Dong Hwang Chen

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A novel heterogeneous magnetic nanocatalyst was designed by conjugating copper(II) ions with chitosan-bound magnetic nanocarrier. Its hydrolytic activity for phosphodiesters was evaluated by investigating the hydrolysis of secondary ester bis-(nitrophenyl) phosphate (BNPP) in aqueous media. The maximum hydrolysis rate of BNPP was observed around the pKa of nanocatalyst which was found to be 12. The kinetic studies revealed that the binding affinity of BNPP to the copper(II)-chelated chitosan magnetic nanocarrier was low as compared to other catalyst systems. However, the rate constants (kcat) and maximum reaction rate (Vmax) were found to be higher with lower activation energy for the developed nanocatalyst. Moreover, the developed nanocatalyst was magnetically recoverable and also had good reusability.

Original languageEnglish
Pages (from-to)601-605
Number of pages5
JournalReactive and Functional Polymers
Volume69
Issue number8
DOIs
Publication statusPublished - 2009 Aug 1

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Environmental Chemistry
  • Biochemistry
  • Chemical Engineering(all)
  • Polymers and Plastics
  • Materials Chemistry

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