Abstract
Anti-human T-lymphotropic virus type I/II (HTLV-I/II) antibodies were screened by particle agglutination test in a total of 66 patients with thalassemia major who received multiple transfusion from paid donors at the Blood Transfusion Hematology Center of Ho Chi Minh City in South Vietnam. HTLV-II infection was confirmed in 6 patients (9.1%) by Western blot analysis and/or polymerase chain reaction. Phylogenetic analysis revealed that long terminal repeat sequences of HTLV-II proviruses from 5 thalassemic patients in Vietnam belonged to the same phylogenetic subgroup of HTLV-IIb as those from intravenous drug abusers in North America and Europe. These data shed light on the route of introducing HTLV-II into Vietnam.
Original language | English |
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Pages (from-to) | 1429-1440 |
Number of pages | 12 |
Journal | Archives of Virology |
Volume | 142 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1997 Aug 5 |
All Science Journal Classification (ASJC) codes
- Virology