TY - JOUR
T1 - Hydrodynamic influences of artificial cilia beating behaviors on micromixing
AU - Chen, Chia Yuan
AU - Hsu, Chun Chieh
AU - Mani, Karthick
AU - Panigrahi, Bivas
N1 - Funding Information:
This study was supported through the Ministry of Science and Technology of Taiwan under Contract No. MOST 104-2221-E-006-169 and No. MOST 102-2221-E-006-297-MY3 (to Chia-Yuan Chen). This work would not be possible without the facility provided by Center for the Micro/Nano Science and Technology, National Cheng Kung University. The research was in part supported by the Ministry of Education, Taiwan, R. O. C. through the Aim for the Top University Project to National Cheng Kung University (NCKU).
Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - In microfluidic applications, the beating behaviors of artificial cilia determine the efficacy of artificial cilia-based micromixers. The same is especially true when the rapid mixing of two fluids with artificial cilia actuation is highly demanded in many biomedical and analytical chemistry contexts. The transient hydrodynamics induced by the diversely dynamic motions of artificial cilia and the associated interactions with surrounding flow fields engender speculation for identifying an ideal trajectory of artificial cilia in an effective micromixing process. Intrigued by this motive, we selected four distinct beating behaviors for comparing micromixing performance. The tangled interactions between the induced flow by artificial cilia and the imposing flow through syringe pump actuation were also documented. A parametric study was performed via a micro-particle image velocimetry technique to elucidate the synergic effects contributed by dominant parameters, such as the beating speed and patterns of artificial cilia. Depth-resolved induced flow patterns through artificial cilia actuation were provided using a computational fluid dynamic method to elucidate how micromixing was achieved in a whole-field point of view. A new microscale flow mixing concept was therefore initiated and demonstrated in this work to extend the current practices related to artificial cilia-based micromixers for highly viscous flow manipulation applications.
AB - In microfluidic applications, the beating behaviors of artificial cilia determine the efficacy of artificial cilia-based micromixers. The same is especially true when the rapid mixing of two fluids with artificial cilia actuation is highly demanded in many biomedical and analytical chemistry contexts. The transient hydrodynamics induced by the diversely dynamic motions of artificial cilia and the associated interactions with surrounding flow fields engender speculation for identifying an ideal trajectory of artificial cilia in an effective micromixing process. Intrigued by this motive, we selected four distinct beating behaviors for comparing micromixing performance. The tangled interactions between the induced flow by artificial cilia and the imposing flow through syringe pump actuation were also documented. A parametric study was performed via a micro-particle image velocimetry technique to elucidate the synergic effects contributed by dominant parameters, such as the beating speed and patterns of artificial cilia. Depth-resolved induced flow patterns through artificial cilia actuation were provided using a computational fluid dynamic method to elucidate how micromixing was achieved in a whole-field point of view. A new microscale flow mixing concept was therefore initiated and demonstrated in this work to extend the current practices related to artificial cilia-based micromixers for highly viscous flow manipulation applications.
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U2 - 10.1016/j.cep.2015.10.023
DO - 10.1016/j.cep.2015.10.023
M3 - Article
AN - SCOPUS:84947073297
SN - 0255-2701
VL - 99
SP - 33
EP - 40
JO - Chemical Engineering and Processing: Process Intensification
JF - Chemical Engineering and Processing: Process Intensification
ER -