@inproceedings{e562224b5be045dca69c97e930bd1e11,
title = "Hyperthermia cancer therapy utilizing superparamagnetic nanoparticles",
abstract = "This paper presents an investigation of hyperthermia cancer therapy utilizing high-frequency magnetic field to induce a temperature increase on tumor cells by using a commercially-available radiography solution containing superparamagnetic nanoparticles. The biocompatible and biodegradable materials allow us to explore hyperthermia cancer therapy in vivo or in vitro. Experimental data showed that a temperature as high as 72.4°C can be successfully generated for in vitro experiments. In-vitro testing showed that survival rate of the tumor cells can be greatly reduced. In-vivo experiments showed that the hyperthermia therapy can significantly repress the growth of liver tumors by utilizing concentrated commercial nanoparticles and temperature-sensitive hydrogel. Hydrogel used in drug delivery system was liquid at low temperature (<20°C) and became gel above 30°C. The gel can be used to secure the nanoparticles in the target tumor tissue. Furthermore, a temperature control system was designed to keep the nanoparticles at a constant temperature such that a reliable cancer therapy can be feasible.",
author = "Tseng, {Hao Yu} and Lee, {Chen Yi} and Shih, {Ying Hsia} and Lin, {Xi Zhang} and Lee, {Gwo Bin}",
year = "2007",
doi = "10.1109/NEMS.2007.352253",
language = "English",
isbn = "1424406102",
series = "Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007",
pages = "163--166",
booktitle = "Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007",
note = "2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 ; Conference date: 16-01-2007 Through 19-01-2007",
}