TY - JOUR
T1 - Hyperventilation-induced ictal fear in nonlesional temporal lobe epilepsy
AU - Yang, Chih Sheng
AU - Chow, Julie Chi
AU - Tsai, Jing Jane
AU - Huang, Chin Wei
N1 - Funding Information:
This work was partly supported by Grant NSC 98-2314-B-006-042-MY2 from the National Science Council, Taiwan .
PY - 2011/5
Y1 - 2011/5
N2 - Hyperventilation is a traditional seizure-provoking procedure used mainly in idiopathic generalized epilepsy and with a relatively limited role in partial epilepsy. Ictal fear is a rare seizure semiology seen in temporal lobe epilepsy. It has been suggested that the amygdala and anterior hippocampus are involved in generating ictal fear. We describe a rare patient with nonlesional temporal epilepsy who, while hyperventilating during an electroencephalography recording, developed complex partial seizures presenting as ictal fear. The particular sensitivity of the anterior hippocampus (probably the amygdala) to hypocapnia might be an important factor contributing to seizures. To avoid misdiagnosing this unusual condition as a pseudo-seizure, a detailed history and seizure semiology, as well as a concurrent electroencephalography recording, are mandatory.
AB - Hyperventilation is a traditional seizure-provoking procedure used mainly in idiopathic generalized epilepsy and with a relatively limited role in partial epilepsy. Ictal fear is a rare seizure semiology seen in temporal lobe epilepsy. It has been suggested that the amygdala and anterior hippocampus are involved in generating ictal fear. We describe a rare patient with nonlesional temporal epilepsy who, while hyperventilating during an electroencephalography recording, developed complex partial seizures presenting as ictal fear. The particular sensitivity of the anterior hippocampus (probably the amygdala) to hypocapnia might be an important factor contributing to seizures. To avoid misdiagnosing this unusual condition as a pseudo-seizure, a detailed history and seizure semiology, as well as a concurrent electroencephalography recording, are mandatory.
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U2 - 10.1016/j.yebeh.2011.02.030
DO - 10.1016/j.yebeh.2011.02.030
M3 - Article
C2 - 21482194
AN - SCOPUS:79955591476
SN - 1525-5050
VL - 21
SP - 100
EP - 102
JO - Epilepsy and Behavior
JF - Epilepsy and Behavior
IS - 1
ER -