Hypothyroidism-Related Hyperprolactinemia: Report of Two Cases and Literature Review

Horng-Yih Ou, Yung Chiang Ma, Eugene Hsin Yu, Ta Jen Wu

Research output: Contribution to journalArticlepeer-review


We report on 2 cases of hyperprolactinemia associated with thyroid dysfunction. The changes in clinical symptoms and serum prolactin levels highly corresponded to thyroxine therapy. The first case had galactorrhea associated with overt hypothyroidism and pituitary microadenoma. All abnormalities disappeared after thyroxine therapy. The second case had galactorrhea resistant to dopamine agonist therapy and demonstrated improvement after thyroxine replacement. Hyperprolactinemia recurred after withdrawal of the dopamine agonist. We review the literature on hypothyroidism-related hyperprolactinemia and discuss the current opinions about this condition.

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalTzu Chi Medical Journal
Issue number6
Publication statusPublished - 2003 Dec

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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