Hypothyroidism-Related Hyperprolactinemia: Report of Two Cases and Literature Review

Horng-Yih Ou; Yung Chiang Ma; Eugene Hsin Yu; Ta Jen Wu

Hypothyroidism-Related Hyperprolactinemia: Report of Two Cases and Literature Review

Horng-Yih Ou, Yung Chiang Ma, Eugene Hsin Yu, Ta Jen Wu

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We report on 2 cases of hyperprolactinemia associated with thyroid dysfunction. The changes in clinical symptoms and serum prolactin levels highly corresponded to thyroxine therapy. The first case had galactorrhea associated with overt hypothyroidism and pituitary microadenoma. All abnormalities disappeared after thyroxine therapy. The second case had galactorrhea resistant to dopamine agonist therapy and demonstrated improvement after thyroxine replacement. Hyperprolactinemia recurred after withdrawal of the dopamine agonist. We review the literature on hypothyroidism-related hyperprolactinemia and discuss the current opinions about this condition.

Original language	English
Pages (from-to)	417-420
Number of pages	4
Journal	Tzu Chi Medical Journal
Volume	15
Issue number	6
Publication status	Published - 2003 Dec

All Science Journal Classification (ASJC) codes

Medicine(all)

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title = "Hypothyroidism-Related Hyperprolactinemia: Report of Two Cases and Literature Review",

abstract = "We report on 2 cases of hyperprolactinemia associated with thyroid dysfunction. The changes in clinical symptoms and serum prolactin levels highly corresponded to thyroxine therapy. The first case had galactorrhea associated with overt hypothyroidism and pituitary microadenoma. All abnormalities disappeared after thyroxine therapy. The second case had galactorrhea resistant to dopamine agonist therapy and demonstrated improvement after thyroxine replacement. Hyperprolactinemia recurred after withdrawal of the dopamine agonist. We review the literature on hypothyroidism-related hyperprolactinemia and discuss the current opinions about this condition.",

author = "Horng-Yih Ou and Ma, {Yung Chiang} and Yu, {Eugene Hsin} and Wu, {Ta Jen}",

year = "2003",

month = dec,

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volume = "15",

pages = "417--420",

journal = "Tzu Chi Medical Journal",

issn = "1016-3190",

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number = "6",

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T2 - Report of Two Cases and Literature Review

AU - Ou, Horng-Yih

AU - Ma, Yung Chiang

AU - Yu, Eugene Hsin

AU - Wu, Ta Jen

PY - 2003/12

Y1 - 2003/12

N2 - We report on 2 cases of hyperprolactinemia associated with thyroid dysfunction. The changes in clinical symptoms and serum prolactin levels highly corresponded to thyroxine therapy. The first case had galactorrhea associated with overt hypothyroidism and pituitary microadenoma. All abnormalities disappeared after thyroxine therapy. The second case had galactorrhea resistant to dopamine agonist therapy and demonstrated improvement after thyroxine replacement. Hyperprolactinemia recurred after withdrawal of the dopamine agonist. We review the literature on hypothyroidism-related hyperprolactinemia and discuss the current opinions about this condition.

AB - We report on 2 cases of hyperprolactinemia associated with thyroid dysfunction. The changes in clinical symptoms and serum prolactin levels highly corresponded to thyroxine therapy. The first case had galactorrhea associated with overt hypothyroidism and pituitary microadenoma. All abnormalities disappeared after thyroxine therapy. The second case had galactorrhea resistant to dopamine agonist therapy and demonstrated improvement after thyroxine replacement. Hyperprolactinemia recurred after withdrawal of the dopamine agonist. We review the literature on hypothyroidism-related hyperprolactinemia and discuss the current opinions about this condition.

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VL - 15

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JO - Tzu Chi Medical Journal

JF - Tzu Chi Medical Journal

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