Impact of influenza vaccination on major cause-specific mortality

Chong Shan Wang; Shan Tair Wang; Ching Te Lai; Li Jen Lin; Pesus Chou

doi:10.1016/j.vaccine.2006.10.015

Impact of influenza vaccination on major cause-specific mortality

Chong Shan Wang, Shan Tair Wang, Ching Te Lai, Li Jen Lin, Pesus Chou

Institute of Gerontology

Research output: Contribution to journal › Article › peer-review

106 Citations (Scopus)

Abstract

The efficacy of influenza vaccination is not well understood for major cause-specific mortality except pneumonia. For 10 months we followed the mortality data of 35,637 vaccinated elderly (>65 years old) in a county with 102,698 elderly in southern Taiwan. A multivariate Cox model showed that vaccination was significantly associated with lower mortality for all causes, [hazards ratio (HR) = 0.56], stroke (HR = 0.35), renal disease (HR = 0.40), diabetes mellitus (HR = 0.45), pneumonia (HR = 0.47), COPD (HR = 0.55), malignancy (HR = 0.74), and heart diseases (HR = 0.78), p < 0.05. Influenza vaccination was strongly associated with reducing major cause-specific mortality.

Original language	English
Pages (from-to)	1196-1203
Number of pages	8
Journal	Vaccine
Volume	25
Issue number	7
DOIs	https://doi.org/10.1016/j.vaccine.2006.10.015
Publication status	Published - 2007 Jan 26

All Science Journal Classification (ASJC) codes

Molecular Medicine
General Immunology and Microbiology
General Veterinary
Public Health, Environmental and Occupational Health
Infectious Diseases

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vaccine.2006.10.015

Cite this

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title = "Impact of influenza vaccination on major cause-specific mortality",

abstract = "The efficacy of influenza vaccination is not well understood for major cause-specific mortality except pneumonia. For 10 months we followed the mortality data of 35,637 vaccinated elderly (>65 years old) in a county with 102,698 elderly in southern Taiwan. A multivariate Cox model showed that vaccination was significantly associated with lower mortality for all causes, [hazards ratio (HR) = 0.56], stroke (HR = 0.35), renal disease (HR = 0.40), diabetes mellitus (HR = 0.45), pneumonia (HR = 0.47), COPD (HR = 0.55), malignancy (HR = 0.74), and heart diseases (HR = 0.78), p < 0.05. Influenza vaccination was strongly associated with reducing major cause-specific mortality.",

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AU - Wang, Chong Shan

AU - Wang, Shan Tair

AU - Lai, Ching Te

AU - Lin, Li Jen

AU - Chou, Pesus

PY - 2007/1/26

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AB - The efficacy of influenza vaccination is not well understood for major cause-specific mortality except pneumonia. For 10 months we followed the mortality data of 35,637 vaccinated elderly (>65 years old) in a county with 102,698 elderly in southern Taiwan. A multivariate Cox model showed that vaccination was significantly associated with lower mortality for all causes, [hazards ratio (HR) = 0.56], stroke (HR = 0.35), renal disease (HR = 0.40), diabetes mellitus (HR = 0.45), pneumonia (HR = 0.47), COPD (HR = 0.55), malignancy (HR = 0.74), and heart diseases (HR = 0.78), p < 0.05. Influenza vaccination was strongly associated with reducing major cause-specific mortality.

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Impact of influenza vaccination on major cause-specific mortality

Abstract

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