TY - GEN
T1 - Impedimetric quantification of the density of suspending Trichomonas vaginalis
AU - Chen, Ming Jei
AU - Huang, Chia Hao
AU - Lei, Kin Fong
AU - Cheng, Wei Hung
AU - Tang, Petrus
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2016/11/28
Y1 - 2016/11/28
N2 - To investigate the chemosensitivity of T. vaginalis under tested drug, quantification of the density of T. vaginalis is necessary to study its viability. However, because T. vaginalis is suspended in the medium, microscopic quantification is not practical. In this work, impedimetric quantification of T. vaginalis was demonstrated using a biosensor. Investigations of impedance spectrum, sample loading volume, and correction between impedance magnitude and density of T. vaginalis were reported. Results showed the feasibility of the quantification of suspending cells based on impedance measurement technique. With the advantage of microfluidics technology, quantification of suspending cells can be completed in less sample volume (30 μl) and fast response (a few seconds). The present work has high potential to apply for the study of the development of therapeutic drug of T. vaginalis.
AB - To investigate the chemosensitivity of T. vaginalis under tested drug, quantification of the density of T. vaginalis is necessary to study its viability. However, because T. vaginalis is suspended in the medium, microscopic quantification is not practical. In this work, impedimetric quantification of T. vaginalis was demonstrated using a biosensor. Investigations of impedance spectrum, sample loading volume, and correction between impedance magnitude and density of T. vaginalis were reported. Results showed the feasibility of the quantification of suspending cells based on impedance measurement technique. With the advantage of microfluidics technology, quantification of suspending cells can be completed in less sample volume (30 μl) and fast response (a few seconds). The present work has high potential to apply for the study of the development of therapeutic drug of T. vaginalis.
UR - http://www.scopus.com/inward/record.url?scp=85007273776&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85007273776&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2016.7758297
DO - 10.1109/NEMS.2016.7758297
M3 - Conference contribution
AN - SCOPUS:85007273776
T3 - 2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016
SP - 490
EP - 493
BT - 2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 11th IEEE Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016
Y2 - 17 April 2016 through 20 April 2016
ER -