In situ tailoring of carbon dots-metal ferrite nanohybrid as multipurpose marker agent of HeLa cancer cells

Siti Febtria Asrini Sugito, Fakhri Firdaus, Yu Aung, Satya Candra Wibawa Sakti, Hsien Tai Chiu, Mochamad Zakki Fahmi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The development of multifunction material was considered to attain effectiveness on cancer treatment. The present study pursues the potential application of metal ferrite nanoparticles covered with CDs to get dual-active nanomaterial on fluorescent and magnetic responses that were prepared on a one-pot solvothermal method. Some analyses indicated the nanohybrids consisted of amorphous structure. Besides, the optical analysis performed optimum emission with QY percentage up to 0.9 and 0.6, respectively. Magnetic response assessment confirmed CDs@MnFe2O4-15 has good superparamagnetic properties with saturation magnetization value of 38.485 emu/g, while CDs@CuFe2O4-15 at 9.5245 emu/g. The DLS measurement showed an average size of CDs@MnFe2O4-45 at 63.98 nm, while CDs@CuFe2O4-45 at 55.46 nm. Then, this nanosized drive to perform good photoluminescent properties and good cytotoxicity due to the nanohybrids of CDs@MFe2O4-45 can easily enter the HeLa cells without harming its original structure. The above finding has well-proven good clinical potency of the nanohybrid as simultaneous fluorescent and magnetic-based detection. Graphical abstract: [Figure not available: see fulltext.]

Original languageEnglish
Pages (from-to)1941-1951
Number of pages11
JournalJournal of Materials Research
Issue number11
Publication statusPublished - 2022 Jun 14

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


Dive into the research topics of 'In situ tailoring of carbon dots-metal ferrite nanohybrid as multipurpose marker agent of HeLa cancer cells'. Together they form a unique fingerprint.

Cite this