TY - JOUR
T1 - In vitro degradation behavior of porous calcium phosphates under diametral compression loading
AU - Ding, Shinn Jyh
AU - Wang, Chien Wen
AU - Chen, David Chan Hen
AU - Chang, Hsien Chang
N1 - Funding Information:
The authors acknowledge with appreciation the support of this research by the National Science Council of the Republic of China under the contract no. NSC 92-2614-E-040-020.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005
Y1 - 2005
N2 - Four different types of porous calcium phosphates were made on addition of a pore-forming compound (PVA) by sinter processing. Mechanical properties, morphology, and weight change with immersion time in Hanks' physiological solution were evaluated. The in vitro fatigue test was also performed. Experimental results showed the pore microstructure of the as-sintered bodies to be made up of the macropores and micropores. The initial strength of the porous bodies was dependent on the contents of the PVA additive. Porous bodies subjected to cycling fatigue in Hanks' solution remarkably decreased in the strength. With increasing immersion time in solution, the tensile strength and elastic modulus of various porous bodies decreased. The weight loss data confirmed the degradation behavior of the porous bodies in Hank's solution. The biomedical uses of the present porous materials are limited to non-load bearing applications such as bone defect repair.
AB - Four different types of porous calcium phosphates were made on addition of a pore-forming compound (PVA) by sinter processing. Mechanical properties, morphology, and weight change with immersion time in Hanks' physiological solution were evaluated. The in vitro fatigue test was also performed. Experimental results showed the pore microstructure of the as-sintered bodies to be made up of the macropores and micropores. The initial strength of the porous bodies was dependent on the contents of the PVA additive. Porous bodies subjected to cycling fatigue in Hanks' solution remarkably decreased in the strength. With increasing immersion time in solution, the tensile strength and elastic modulus of various porous bodies decreased. The weight loss data confirmed the degradation behavior of the porous bodies in Hank's solution. The biomedical uses of the present porous materials are limited to non-load bearing applications such as bone defect repair.
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U2 - 10.1016/j.ceramint.2004.08.007
DO - 10.1016/j.ceramint.2004.08.007
M3 - Article
AN - SCOPUS:15844390941
VL - 31
SP - 691
EP - 696
JO - Ceramics International
JF - Ceramics International
SN - 0272-8842
IS - 5
ER -