Abstract
We found that a carbonic anhydrase, YadF, is essential for cell growth in the absence of another carbonic anhydrase, CynT, in Escherichia coli. However, mutant strains lacking both of them grew at high CO2 concentrations (5%), where non-enzymatic mechanisms generate HCO3−. This suggests that these carbonic anhydrases are essential because they maintain HCO3− levels at ambient CO2 concentrations.
| Original language | English |
|---|---|
| Pages (from-to) | 919-922 |
| Number of pages | 4 |
| Journal | Bioscience, Biotechnology and Biochemistry |
| Volume | 67 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2003 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry
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Indispensability of the Escherichia coli Carbonic Anhydrases YadF and CynT in Cell Proliferation at a Low CO2 Partial Pressure. / Hashimoto, Masayuki; Kato, Jun Ichi.
In: Bioscience, Biotechnology and Biochemistry, Vol. 67, No. 4, 01.01.2003, p. 919-922.Research output: Contribution to journal › Article
TY - JOUR
T1 - Indispensability of the Escherichia coli Carbonic Anhydrases YadF and CynT in Cell Proliferation at a Low CO2 Partial Pressure
AU - Hashimoto, Masayuki
AU - Kato, Jun Ichi
PY - 2003/1/1
Y1 - 2003/1/1
N2 - We found that a carbonic anhydrase, YadF, is essential for cell growth in the absence of another carbonic anhydrase, CynT, in Escherichia coli. However, mutant strains lacking both of them grew at high CO2 concentrations (5%), where non-enzymatic mechanisms generate HCO3−. This suggests that these carbonic anhydrases are essential because they maintain HCO3− levels at ambient CO2 concentrations.
AB - We found that a carbonic anhydrase, YadF, is essential for cell growth in the absence of another carbonic anhydrase, CynT, in Escherichia coli. However, mutant strains lacking both of them grew at high CO2 concentrations (5%), where non-enzymatic mechanisms generate HCO3−. This suggests that these carbonic anhydrases are essential because they maintain HCO3− levels at ambient CO2 concentrations.
UR - http://www.scopus.com/inward/record.url?scp=0041819505&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0041819505&partnerID=8YFLogxK
U2 - 10.1271/bbb.67.919
DO - 10.1271/bbb.67.919
M3 - Article
VL - 67
SP - 919
EP - 922
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 4
ER -