Infantile hemangioendothelioma with a highly elevated serum alpha-fetoprotein level

Shu Jen Han, Chien Chung Tsai, Hong-Ming Tsai, Yung Jung Chen

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Infantile hemangioendothelioma is the meet common vascular tumor in infancy. A three-month-old infant was admitted to the hospital for hepatomegaly. Abdominal ultrasonography, a CT-scan, and MRI studies demonstrated bilateral diffuse hepatic nodules, which were characteristic of hepatic hemangioendothelioma. A highly elevated alpha-fetoprotein (AFP) level misled us to an impression of hepatoblastoma, but the pathology report through an open biopsy disclosed a liver hemangioendothelioma. The patient responded to methylprednisolone therapy. A follow-up sonogram revealed regression of the hepatic masses. This case emphasizes that an elevated AFP level of up to 400 ng/ml is normally found in some neonates until two months of age. Careful interpretation of this value is very important, especially when it is associated with a hepatic tumor. Herein, we present a case of infantile hemangioendothelioma in a three-month-old boy with a highly elevated serum AFP.

Original languageEnglish
Pages (from-to)459-461
Number of pages3
JournalHepato-Gastroenterology
Volume45
Issue number20
Publication statusPublished - 1998 Apr 27

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Hemangioendothelioma
alpha-Fetoproteins
Liver
Serum
Hepatoblastoma
Hepatomegaly
Methylprednisolone
Blood Vessels
Ultrasonography
Neoplasms
Magnetic Resonance Imaging
Newborn Infant
Pathology
Biopsy

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Han, Shu Jen ; Tsai, Chien Chung ; Tsai, Hong-Ming ; Chen, Yung Jung. / Infantile hemangioendothelioma with a highly elevated serum alpha-fetoprotein level. In: Hepato-Gastroenterology. 1998 ; Vol. 45, No. 20. pp. 459-461.
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Infantile hemangioendothelioma with a highly elevated serum alpha-fetoprotein level. / Han, Shu Jen; Tsai, Chien Chung; Tsai, Hong-Ming; Chen, Yung Jung.

In: Hepato-Gastroenterology, Vol. 45, No. 20, 27.04.1998, p. 459-461.

Research output: Contribution to journalArticle

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